MB0164

antibody from Bioworld Technology, Inc

Targeting: RPA1 HSSB, REPA1, RF-A, RP-A, RPA70

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

MB0164

Provider

Bioworld Technology, Inc

Product name

RPA1 monoclonal antibody

Antibody type

Monoclonal

Antigen

Recombinant full length Human RPA1.

Description

Plays an essential role in several cellular processes in DNA metabolism including replication,recombination and DNA repair.Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair;it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro,aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC),the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Reactivity

Human, Mouse, Rat, Simian

Host

Mouse

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Western blot

Supportive validation

Submitted by

Bioworld Technology, Inc (provider)

Main image

Experimental details

Western blot detection of RPA70 antibody in Hela, 293T, C6, 3T3 and K562 cell lysates using RPA70 antibody (1:1000 diluted) .