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LearnABIN1002344
antibody from antibodies-online
Targeting: GFRA1
GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations [0]
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- Product number
- ABIN1002344 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-GDNF Family Receptor alpha 1 (GFRA1) (Internal Region) antibody
- Antibody type
- Polyclonal
- Antigen
- Rabbit polyclol GFR-1 antibody was raised against a peptide corresponding to amino acids 369 to 382 of human GFR-1 .
- Description
- Antibody is purified via DEAE-column chromatography.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Internal Region
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.
Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins.
GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF.
Characterization of a multicomponent receptor for GDNF.
Buj-Bello A, Adu J, Piñón LG, Horton A, Thompson J, Rosenthal A, Chinchetru M, Buchman VL, Davies AM
Nature 1997 Jun 12;387(6634):721-4
Nature 1997 Jun 12;387(6634):721-4
Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins.
Sanicola M, Hession C, Worley D, Carmillo P, Ehrenfels C, Walus L, Robinson S, Jaworski G, Wei H, Tizard R, Whitty A, Pepinsky RB, Cate RL
Proceedings of the National Academy of Sciences of the United States of America 1997 Jun 10;94(12):6238-43
Proceedings of the National Academy of Sciences of the United States of America 1997 Jun 10;94(12):6238-43
GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF.
Jing S, Wen D, Yu Y, Holst PL, Luo Y, Fang M, Tamir R, Antonio L, Hu Z, Cupples R, Louis JC, Hu S, Altrock BW, Fox GM
Cell 1996 Jun 28;85(7):1113-24
Cell 1996 Jun 28;85(7):1113-24
Characterization of a multicomponent receptor for GDNF.
Treanor JJ, Goodman L, de Sauvage F, Stone DM, Poulsen KT, Beck CD, Gray C, Armanini MP, Pollock RA, Hefti F, Phillips HS, Goddard A, Moore MW, Buj-Bello A, Davies AM, Asai N, Takahashi M, Vandlen R, Henderson CE, Rosenthal A
Nature 1996 Jul 4;382(6586):80-3
Nature 1996 Jul 4;382(6586):80-3
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