ABIN1673217

antibody from antibodies-online

Targeting: GZMB CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN1673217

Provider

antibodies-online

Product name

anti-Granzyme B (Granzyme 2, Cytotoxic T-Lymphocyte-Associated serine Esterase 1) (Gzmb) (C-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the C-terminal of human Granzyme B.Immunogen affinity purified.

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

A novel NF-kappaB binding site controls human granzyme B gene transcription.

Huang C, Bi E, Hu Y, Deng W, Tian Z, Dong C, Hu Y, Sun B
Journal of immunology (Baltimore, Md. : 1950) 2006 Apr 1;176(7):4173-81

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Aberrant recombination involving the granzyme locus occurs in Atm-/- T-cell lymphomas.

Winrow CJ, Pankratz DG, Vibat CR, Bowen TJ, Callahan MA, Warren AJ, Hilbush BS, Wynshaw-Boris A, Hasel KW, Weaver Z, Lockhart DJ, Barlow C
Human molecular genetics 2005 Sep 15;14(18):2671-84

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Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.

Motyka B, Korbutt G, Pinkoski MJ, Heibein JA, Caputo A, Hobman M, Barry M, Shostak I, Sawchuk T, Holmes CF, Gauldie J, Bleackley RC
Cell 2000 Oct 27;103(3):491-500