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LearnHPA003418
antibody from Atlas Antibodies
Targeting: GZMB
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- HPA003418 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA003418, RRID:AB_1079020
- Product name
- Anti-GZMB
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human GZMB, Gene description: granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), Alternative Gene Names: CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT, Validated applications: IHC, WB, Uniprot ID: P10144, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.05 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Defining early SIV replication and dissemination dynamics following vaginal transmission
Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence
Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8 + T cells
The progression of CD56+ myeloid sarcoma: A case report and literature review
Deleage C, Immonen T, Fennessey C, Reynaldi A, Reid C, Newman L, Lipkey L, Schlub T, Camus C, O’Brien S, Smedley J, Conway J, Del Prete G, Davenport M, Lifson J, Estes J, Keele B
Science Advances 2019;5(5)
Science Advances 2019;5(5)
Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence
Bangham C, Pino M, Paganini S, Deleage C, Padhan K, Harper J, King C, Micci L, Cervasi B, Mudd J, Gill K, Jean S, Easley K, Silvestri G, Estes J, Petrovas C, Lederman M, Paiardini M
PLOS Pathogens 2019;15(10):e1008081
PLOS Pathogens 2019;15(10):e1008081
Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8 + T cells
Nguyen S, Deleage C, Darko S, Ransier A, Truong D, Agarwal D, Japp A, Wu V, Kuri-Cervantes L, Abdel-Mohsen M, Del Rio Estrada P, Ablanedo-Terrazas Y, Gostick E, Hoxie J, Zhang N, Naji A, Reyes-Terán G, Estes J, Price D, Douek D, Deeks S, Buggert M, Betts M
Science Translational Medicine 2019;11(523)
Science Translational Medicine 2019;11(523)
The progression of CD56+ myeloid sarcoma: A case report and literature review
WANG X, LI W, ZHENG Y, YING Z, WANG Y, WANG Y, ZHENG J, XIAO S
Oncology Letters 2016;11(5):3091-3096
Oncology Letters 2016;11(5):3091-3096
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and gZMB over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY401332).
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human lymph node and skeletal muscle tissues using HPA003418 antibody. Corresponding GZMB RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
