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- References [5]
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- Immunocytochemistry [1]
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- Product number
- 24721-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- MDC1 antibody
- Antibody type
- Polyclonal
- Description
- MDC1 antibody (Cat. #24721-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The male pachynema-specific protein MAPS drives phase separation in vitro and regulates sex body formation and chromatin behaviors in vivo.
Functional defects of cancer-associated MDC1 mutations in DNA damage repair.
A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination.
SFN Enhanced the Radiosensitivity of Cervical Cancer Cells via Activating LATS2 and Blocking Rad51/MDC1 Recruitment to DNA Damage Site.
Wnt signaling induces radioresistance through upregulating HMGB1 in esophageal squamous cell carcinoma.
Lin Z, Li D, Zheng J, Yao C, Liu D, Zhang H, Feng H, Chen C, Li P, Zhang Y, Jiang B, Hu Z, Zhao Y, Shi F, Cao D, Rodriguez-Wallberg KA, Li Z, Yeung WSB, Chow LT, Wang H, Liu K
Cell reports 2024 Jan 23;43(1):113651
Cell reports 2024 Jan 23;43(1):113651
Functional defects of cancer-associated MDC1 mutations in DNA damage repair.
Xie R, Yan Z, Jing J, Wang Y, Zhang J, Li Y, Liu X, Yu X, Wu C
DNA repair 2022 Jun;114:103330
DNA repair 2022 Jun;114:103330
A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination.
Zhao J, Tian S, Guo Q, Bao K, Yu G, Wang X, Shen X, Zhang J, Chen J, Yang Y, Liu L, Li X, Hao J, Yang N, Liu Z, Ai D, Yang J, Zhu Y, Yao Z, Ma S, Zhang K, Shi L
Molecular cell 2022 Jul 21;82(14):2571-2587.e9
Molecular cell 2022 Jul 21;82(14):2571-2587.e9
SFN Enhanced the Radiosensitivity of Cervical Cancer Cells via Activating LATS2 and Blocking Rad51/MDC1 Recruitment to DNA Damage Site.
Wang S, Wang Y, Liu X, Yang Y, Wu S, Liu Y
Cancers 2022 Apr 8;14(8)
Cancers 2022 Apr 8;14(8)
Wnt signaling induces radioresistance through upregulating HMGB1 in esophageal squamous cell carcinoma.
Zhao Y, Yi J, Tao L, Huang G, Chu X, Song H, Chen L
Cell death & disease 2018 Apr 1;9(4):433
Cell death & disease 2018 Apr 1;9(4):433
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MDC1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MDC1. This antibody recognizes human antigen. The MDC1 antibody has been validated for the following applications: ELISA, IHC, IF analysis.
