FNab05072

antibody from FineTest Biotech

Targeting: MDC1 Em:AB023051.5, KIAA0170, NFBD1

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab05072 - Provider product page
Provider: FineTest Biotech
Product name: MDC1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: mediator of DNA damage checkpoint 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)

MDC1 protein structure - FNab05072 shown in red.