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LearnHPA006735
antibody from Atlas Antibodies
Targeting: TASOR
C3orf63, FAM208A, KIAA1105, RAP140, se89-1, TASOR1
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations [0]
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- Product number
- HPA006735 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA006735, RRID:AB_1852384
- Product name
- Anti-FAM208A
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human FAM208A, Gene description: family with sequence similarity 208, member A, Alternative Gene Names: C3orf63, KIAA1105, RAP140, se89-1, Validated applications: IHC, Uniprot ID: Q9UK61, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Autonomous transposons tune their sequences to ensure somatic suppression
DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor
Interplay between Two Paralogous Human Silencing Hub (HuSH) Complexes in Regulating LINE-1 Element Silencing
Characterization of Hepatoma-Derived Growth Factor-Related Protein 2 Interactions with Heterochromatin
The DUF3715 domain has a conserved role in RNA-directed transposon silencing.
Epigenetic Silencing of Recombinant Adeno-associated Virus Genomes by NP220 and the HUSH Complex
HUSH-mediated HIV silencing is independent of TASOR phosphorylation on threonine 819
Genome surveillance by HUSH-mediated silencing of intronless mobile elements
Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx
A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2’s Association with the HUSH Complex
Periphilin self-association underpins epigenetic silencing by the HUSH complex
TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells
Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection.
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators.
Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2.
Characterization of a core region in the A2UCOE that confers effective anti-silencing activity.
Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
Ilık İ, Glažar P, Tse K, Brändl B, Meierhofer D, Müller F, Smith Z, Aktaş T
Nature 2024;626(8001):1116-1124
Nature 2024;626(8001):1116-1124
DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor
Pandiloski N, Horváth V, Karlsson O, Koutounidou S, Dorazehi F, Christoforidou G, Matas-Fuentes J, Gerdes P, Garza R, Jönsson M, Adami A, Atacho D, Johansson J, Englund E, Kokaia Z, Jakobsson J, Douse C
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
Interplay between Two Paralogous Human Silencing Hub (HuSH) Complexes in Regulating LINE-1 Element Silencing
Jensvold Z, Flood J, Christenson A, Lewis P
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
Characterization of Hepatoma-Derived Growth Factor-Related Protein 2 Interactions with Heterochromatin
Wistner S, MacDonald I, Stanley K, Hathaway N
Cells 2023;12(2):325
Cells 2023;12(2):325
The DUF3715 domain has a conserved role in RNA-directed transposon silencing.
Schöpp T, Prigozhin DM, Douse C, Kaji K, Cook AG, O'Carroll D
RNA (New York, N.Y.) 2023 Oct;29(10):1471-1480
RNA (New York, N.Y.) 2023 Oct;29(10):1471-1480
Epigenetic Silencing of Recombinant Adeno-associated Virus Genomes by NP220 and the HUSH Complex
Das A, Vijayan M, Walton E, Stafford V, Fiflis D, Asokan A, Sandri-Goldin R
Journal of Virology 2022;96(4)
Journal of Virology 2022;96(4)
HUSH-mediated HIV silencing is independent of TASOR phosphorylation on threonine 819
Vauthier V, Lasserre A, Morel M, Versapuech M, Berlioz-Torrent C, Zamborlini A, Margottin-Goguet F, Matkovic R
Retrovirology 2022;19(1)
Retrovirology 2022;19(1)
Genome surveillance by HUSH-mediated silencing of intronless mobile elements
Seczynska M, Bloor S, Cuesta S, Lehner P
Nature 2021;601(7893):440-445
Nature 2021;601(7893):440-445
Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx
Johnson W, Martin M, Matkovic R, Larrous P, Morel M, Lasserre A, Vauthier V, Margottin-Goguet F
PLOS Pathogens 2021;17(10):e1009609
PLOS Pathogens 2021;17(10):e1009609
A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2’s Association with the HUSH Complex
Waybright J, Clinkscales S, Barnash K, Budziszewski G, Rectenwald J, Chiarella A, Norris-Drouin J, Cholensky S, Pearce K, Herring L, McGinty R, Hathaway N, James L
ACS Chemical Biology 2021;16(9):1721-1736
ACS Chemical Biology 2021;16(9):1721-1736
Periphilin self-association underpins epigenetic silencing by the HUSH complex
Prigozhin D, Douse C, Farleigh L, Albecka A, Tchasovnikarova I, Timms R, Oda S, Adolf F, Freund S, Maslen S, Lehner P, Modis Y
Nucleic Acids Research 2020;48(18):10313-10328
Nucleic Acids Research 2020;48(18):10313-10328
TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
Douse C, Tchasovnikarova I, Timms R, Protasio A, Seczynska M, Prigozhin D, Albecka A, Wagstaff J, Williamson J, Freund S, Lehner P, Modis Y
Nature Communications 2020;11(1)
Nature Communications 2020;11(1)
HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells
Yan J, Shun M, Zhang Y, Hao C, Skowronski J
Proceedings of the National Academy of Sciences 2019;116(19):9568-9577
Proceedings of the National Academy of Sciences 2019;116(19):9568-9577
Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection.
Greenwood EJD, Williamson JC, Sienkiewicz A, Naamati A, Matheson NJ, Lehner PJ
Cell reports 2019 Apr 30;27(5):1579-1596.e7
Cell reports 2019 Apr 30;27(5):1579-1596.e7
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators.
Liu N, Lee CH, Swigut T, Grow E, Gu B, Bassik MC, Wysocka J
Nature 2018 Jan 11;553(7687):228-232
Nature 2018 Jan 11;553(7687):228-232
Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2.
Tchasovnikarova IA, Timms RT, Douse CH, Roberts RC, Dougan G, Kingston RE, Modis Y, Lehner PJ
Nature genetics 2017 Jul;49(7):1035-1044
Nature genetics 2017 Jul;49(7):1035-1044
Characterization of a core region in the A2UCOE that confers effective anti-silencing activity.
Zhang F, Santilli G, Thrasher AJ
Scientific reports 2017 Aug 31;7(1):10213
Scientific reports 2017 Aug 31;7(1):10213
Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
Tchasovnikarova I, Timms R, Matheson N, Wals K, Antrobus R, Göttgens B, Dougan G, Dawson M, Lehner P
Science 2015;348(6242):1481-1485
Science 2015;348(6242):1481-1485
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