12292-1-AP

antibody from Proteintech Group

Targeting: ALKBH3 DEPC-1

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

12292-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#12292-1-AP, RRID:AB_11125161

Product name

ALKBH3 antibody

Antibody type

Polyclonal

Description

KD/KO validated ALKBH3 antibody (Cat. #12292-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Site-Specific Mitochondrial RNA N1-Methyladenosine Demethylation via an Engineered MTS-PUF-ALKBH3 Fusion Protein.

Li X, Kong D, Liu H, Yang J, Zhou J, Qian Y, Zhao D, Li J, Wu X, Zhang T, Sun X, Han Y, Lai L, Li Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e10482

---

Histone modification-regulated LncRNA DLEU1 interacts with ASCC2/ALKBH3 complex to drive DNA repair, antioxidant homeostasis and glucose metabolism in gastric cancer.

Zhang X, Wang X, Wang Q, Wang X, Sun H, Liu Y, Tan C, Ni S, Weng W, Zhang M, Wang L, Huang D, Chen J, Wang X, Gan L, Abudurexiti M, Wang W, Chang J, Sheng W, Xu M
Biomarker research 2026 Jan 2;14(1):1

---

Integrative epitranscriptomic and transcriptomic characterization in human colorectal cancer.

Gong T, Rai SK, Zhu Y, Wang Y, Chen Y, Ma L, Wei X, Ling Z, Pandey A, Qin Y, Huo M, Jijiwa M, Nasu M, Zhang Z, Chen S, Gao Z, Hu X, Nakastu K, Yang H, Fu Y, Wu L, Huang G, Fei P, Deng Y
Journal of advanced research 2025 Sep 21;

---

Quantifying the mRNA epitranscriptome reveals epitranscriptome signatures and roles in cancer.

Feng Y, He X, Guo M, Tang Y, Qi G, Huang Q, Ma W, Chen H, Qin Y, Li R, Wang J, Liu Y
Cellular and molecular life sciences : CMLS 2025 Jul 28;82(1):290

---

m(1)A demethylase Alkbh3 regulates neurogenesis through m(1)A demethylation of Mmp15 mRNA.

Wang H, Xie L, Guo H, Li L, Chen S, Fan Y, Tian J, Xu L, Kong X, Xuan A
Cell & bioscience 2024 Jul 14;14(1):92

---

Evaluation of ALKBH2 and ALKBH3 gene regulation in patients with adult T-cell leukemia/lymphoma.

Wada Y, Naito T, Fukushima T, Saito M
Virology journal 2024 Dec 4;21(1):316

---

PUS7-dependent pseudouridylation of ALKBH3 mRNA inhibits gastric cancer progression.

Chang Y, Jin H, Cui Y, Yang F, Chen K, Kuang W, Huo C, Xu Z, Li Y, Lin A, Yang B, Liu W, Xie S, Zhou T
Clinical and translational medicine 2024 Aug;14(8):e1811

---

The Roles of AGTRAP, ALKBH3, DIVERSIN, NEDD8 and RRM1 in Glioblastoma Pathophysiology and Prognosis.

Dumitru CA, Walter N, Siebert CLR, Schäfer FTA, Rashidi A, Neyazi B, Stein KP, Mawrin C, Sandalcioglu IE
Biomedicines 2024 Apr 22;12(4)

---

Association of AlkB homolog 3 expression with tumor recurrence and unfavorable prognosis in hepatocellular carcinoma.

Wang Q, Wang G, Wang Y, Liu C, He X
Journal of gastroenterology and hepatology 2018 Feb 7;

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

mouse heart tissue were subjected to SDS PAGE followed by western blot with 12292-1-AP(ALKBH3 antibody) at dilution of 1:1000

Sample type

tissue

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human lung cancer using 12292-1-AP(ALKBH3 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The ALKBH3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ALKBH3. This antibody recognizes human, mouse antigen. The ALKBH3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.

Appendix

12292-1-AP.pdf

Show more