BS6318

antibody from Bioworld Technology, Inc
Targeting: AGPAT2 BSCL, LPAAT-beta
Provider product page for BS6318
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6318 - Provider product page
Provider
Bioworld Technology, Inc
Product name
AGPAT2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human AGPAT2.
Description
Phosphatidic acid and lysophosphatidic acid are phospholipids involved in lipid biosynthesis and signal transduction. LPAAT-ÉÇ (lysophosphatidic acid acyltransferase, beta), also known as AGPAT2, BSCL, BSCL1, LPAAB or 1-AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2), is a multi-pass membrane protein localized to the endoplasmic reticulum that catalyzes the synthesis of phosphatidic acid from lysophosphatidic acid. Predominantly expressed in heart and liver, LPAAT-ÉÇ belongs to the LPAAT family of proteins that have a well-known role in lipid biosynthesis. In addition, LPAAT family members may also play a role in tumor progression. Mutations in the gene encoding LPAAT-ÉÇ can result in the autosomal recessive disorder CGL1 (congenital generalized lipodystrophy type 1). CGL1, also known as Berardinelli-Seip congenital lipodystrophy type 1 (BSCL1), is a disorder characterized by insulin resistance, early onset of diabetes, hepatic steatosis, scarcity of adipose tissue and hypertriglyceridemia.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
AGPAT2 protein structure - BS6318 shown in red.