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- References [13]
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- Validations
- Western blot [1]
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- Product number
- 15924-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15924-1-AP, RRID:AB_2285084
- Product name
- RHEB antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RHEB antibody (Cat. #15924-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/A9.
LOXL3 Inhibits Autophagy of Chondrocytes by Activating Rheb in Osteoarthritis.
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
PPT1 Reduction Contributes to Erianin-Induced Growth Inhibition in Oral Squamous Carcinoma Cells.
Rheb1 promotes glucose-stimulated insulin secretion in human and mouse β-cells by upregulating GLUT expression.
MYH9 is crucial for stem cell-like properties in non-small cell lung cancer by activating mTOR signaling.
RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity.
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
CircRNA-100338 Is Associated With mTOR Signaling Pathway and Poor Prognosis in Hepatocellular Carcinoma.
A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II.
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Rheb phosphorylation is involved in p38-regulated/activated protein kinase-mediated tumor suppression in liver cancer.
Crosstalk between glucocorticoid receptor and nutritional sensor mTOR in skeletal muscle.
Wang T, Zhao C, Zhang J, Li S, Zhang Y, Gong Y, Zhou Y, Yan L, Zhang S, Zhang Z, Hu H, Liu A, Bai X, Zou Z
iScience 2024 Feb 16;27(2):108857
iScience 2024 Feb 16;27(2):108857
LOXL3 Inhibits Autophagy of Chondrocytes by Activating Rheb in Osteoarthritis.
Zheng GP, Liu C, Zhang L, Zhong Q, Zhang Y, Huang ZM
Current medical science 2023 Dec;43(6):1195-1200
Current medical science 2023 Dec;43(6):1195-1200
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Jin C, Ou Q, Chen J, Wang T, Zhang J, Wang Z, Wang Y, Tian H, Xu JY, Gao F, Wang J, Li J, Lu L, Xu GT
Stem cell research & therapy 2022 Apr 1;13(1):136
Stem cell research & therapy 2022 Apr 1;13(1):136
PPT1 Reduction Contributes to Erianin-Induced Growth Inhibition in Oral Squamous Carcinoma Cells.
Luo Q, Li X, Gan G, Yang M, Chen X, Chen F
Frontiers in cell and developmental biology 2021;9:764263
Frontiers in cell and developmental biology 2021;9:764263
Rheb1 promotes glucose-stimulated insulin secretion in human and mouse β-cells by upregulating GLUT expression.
Yang Y, Cai Z, Pan Z, Liu F, Li D, Ji Y, Zhong J, Luo H, Hu S, Song L, Yu S, Li T, Li J, Ma X, Zhang W, Zhou Z, Liu F, Zhang J
Metabolism: clinical and experimental 2021 Oct;123:154863
Metabolism: clinical and experimental 2021 Oct;123:154863
MYH9 is crucial for stem cell-like properties in non-small cell lung cancer by activating mTOR signaling.
Chen M, Sun LX, Yu L, Liu J, Sun LC, Yang ZH, Shu X, Ran YL
Cell death discovery 2021 Oct 11;7(1):282
Cell death discovery 2021 Oct 11;7(1):282
RHEB/mTOR hyperactivity causes cortical malformations and epileptic seizures through increased axonal connectivity.
Proietti Onori M, Koene LMC, Schäfer CB, Nellist M, de Brito van Velze M, Gao Z, Elgersma Y, van Woerden GM
PLoS biology 2021 May;19(5):e3001279
PLoS biology 2021 May;19(5):e3001279
Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells.
Chen X, Zhang D, Wang Y, Chen K, Zhao L, Xu Y, Jiang H, Wang S
Cell death & disease 2020 May 28;11(5):402
Cell death & disease 2020 May 28;11(5):402
CircRNA-100338 Is Associated With mTOR Signaling Pathway and Poor Prognosis in Hepatocellular Carcinoma.
Huang XY, Huang ZL, Zhang PB, Huang XY, Huang J, Wang HC, Xu B, Zhou J, Tang ZY
Frontiers in oncology 2019;9:392
Frontiers in oncology 2019;9:392
A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II.
Zhao S, Li Z, Zhang M, Zhang L, Zheng H, Ning J, Wang Y, Wang F, Zhang X, Gan H, Wang Y, Zhang X, Luo H, Bu G, Xu H, Yao Y, Zhang YW
Experimental & molecular medicine 2019 Jul 23;51(7):1-11
Experimental & molecular medicine 2019 Jul 23;51(7):1-11
Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway.
Lv J, Yang L, Guo R, Shi Y, Zhang Z, Ye J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(4):1436-1448
Rheb phosphorylation is involved in p38-regulated/activated protein kinase-mediated tumor suppression in liver cancer.
Zheng M, Zang S, Xie L, Fang X, Zhang YU, Ma X, Liu J, Lin D, Huang A
Oncology letters 2015 Sep;10(3):1655-1661
Oncology letters 2015 Sep;10(3):1655-1661
Crosstalk between glucocorticoid receptor and nutritional sensor mTOR in skeletal muscle.
Shimizu N, Yoshikawa N, Ito N, Maruyama T, Suzuki Y, Takeda S, Nakae J, Tagata Y, Nishitani S, Takehana K, Sano M, Fukuda K, Suematsu M, Morimoto C, Tanaka H
Cell metabolism 2011 Feb 2;13(2):170-82
Cell metabolism 2011 Feb 2;13(2):170-82
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RHEB antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RHEB. This antibody recognizes human antigen. The RHEB antibody has been validated for the following applications: ELISA, WB analysis.
