Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1003087 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ras Homolog Enriched in Brain (RHEB) (Internal Region) antibody
- Antibody type
- Polyclonal
- Antigen
- Rabbit polyclol Rheb antibody was raised against a 15 amino acid peptide from the middle region of human Rheb (Genbank accession No. AAH16155).
- Description
- Affinity chromatography purified via peptide column.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Internal Region
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- 4°C
- Handling
- Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.
Submitted references Rheb is an essential regulator of S6K in controlling cell growth in Drosophila.
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.
rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein.
Stocker H, Radimerski T, Schindelholz B, Wittwer F, Belawat P, Daram P, Breuer S, Thomas G, Hafen E
Nature cell biology 2003 Jun;5(6):559-65
Nature cell biology 2003 Jun;5(6):559-65
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Inoki K, Li Y, Xu T, Guan KL
Genes & development 2003 Aug 1;17(15):1829-34
Genes & development 2003 Aug 1;17(15):1829-34
Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.
Yee WM, Worley PF
Molecular and cellular biology 1997 Feb;17(2):921-33
Molecular and cellular biology 1997 Feb;17(2):921-33
rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein.
Yamagata K, Sanders LK, Kaufmann WE, Yee W, Barnes CA, Nathans D, Worley PF
The Journal of biological chemistry 1994 Jun 10;269(23):16333-9
The Journal of biological chemistry 1994 Jun 10;269(23):16333-9
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