14026-1-AP

antibody from Proteintech Group

Targeting: ZEB2 KIAA0569, SIP-1, SIP1, ZFHX1B

Provider product page for 14026-1-AP

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [64]
Comments [0]
Validations [0]

Submit

Product number: 14026-1-AP - Provider product page
Provider: Proteintech Group
Product name: ZEB2 antibody
Antibody type: Polyclonal
Description: KD/KO validated ZEB2 antibody (Cat. #14026-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ZEB2 protein structure - 14026-1-AP shown in red.

Submitted references FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation.

Xu X, Zhuang X, Yu H, Li P, Li X, Lin H, Teoh JP, Chen Y, Yang Y, Cheng Y, Chen W, Fu X
Theranostics 2024;14(5):2151-2166

Conserved regulatory switches for the transition from natal down to juvenile feather in birds.

Chen CK, Chang YM, Jiang TX, Yue Z, Liu TY, Lu J, Yu Z, Lin JJ, Vu TD, Huang TY, Harn HI, Ng CS, Wu P, Chuong CM, Li WH
Nature communications 2024 May 16;15(1):4174

Hypoxia-inducible factor 3α1 increases epithelial-to-mesenchymal transition and iron uptake to drive colorectal cancer liver metastasis.

Villareal LB, Falcon DM, Xie L, Xue X
British journal of cancer 2024 Jun;130(12):1904-1915

FLNA overexpression promotes papillary thyroid cancer aggression via the FAK/AKT signaling pathway.

Liang W, Zhang Y, Guo Y, Zhang P, Jin J, Guan H, Li Y
Endocrine connections 2024 Jun 1;13(6)

Sinensetin suppresses breast cancer cell progression via Wnt/β-catenin pathway inhibition.

Zhu S, Meng L, Wei P, Gu G, Duan K
Translational cancer research 2024 Jan 31;13(1):348-362

Exosomal circ_0037104 derived from Hu-MSCs inhibits cholangiocarcinoma progression by sponging miR-620 and targeting AFAP1.

Yuan Z, Xiong B, Liu L, Lu Y, Liu Y, Wang G, Qian Y, Diao B, Tu M
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23656

A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation.

Chen L, Xu G, Song X, Zhang L, Chen C, Xiang G, Wang S, Zhang Z, Wu F, Yang X, Zhang L, Ma X, Yu J
Cancer letters 2024 Feb 28;583:216635

ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.

Wang H, Lin F, Xu Z, Yu S, Li G, Liao S, Zhao W, Zhang F, Wang J, Wang S, Ouyang C, Zhang C, Xia H, Wu Y, Jiang B, Li Q
Cellular and molecular gastroenterology and hepatology 2023;16(4):541-556

LOXL1 and LOXL4 are novel target genes of the Zn(2+)-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells.

Hirabayashi D, Yamamoto KI, Maruyama A, Tomonobu N, Kinoshita R, Chen Y, Komalasari NLGY, Murata H, Gohara Y, Jiang F, Zhou J, Ruma IMW, Sumardika IW, Yamauchi A, Kuribayashi F, Toyooka S, Inoue Y, Sakaguchi M
Frontiers in oncology 2023;13:1142886

Transition from natal downs to juvenile feathers: conserved regulatory switches in Neoaves.

Li WH, Chuong CM, Chen CK, Wu P, Jiang TX, Harn HI, Liu TY, Yu Z, Lu J, Chang YM, Yue Z, Lin J, Vu TD, Huang TY, Ng CS
Research square 2023 Oct 3;

Long noncoding RNA MALAT1 inhibition attenuates sepsis-induced acute lung injury through modulating the miR-129-5p/PAX6/ZEB2 axis.

Li Y, Xiao W, Lin X
Microbiology and immunology 2023 Mar;67(3):142-153

MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC.

Zhao K, Zheng M, Su Z, Ghosh S, Zhang C, Zhong W, Ho JWK, Jin G, Zhou Z
Cell reports 2023 Aug 29;42(8):112939

LncRNA n339260 functions in hepatocellular carcinoma progression via regulation of miRNA30e-5p/TP53INP1 expression.

Liu T, Liao S, Mo J, Bai X, Li Y, Zhang Y, Zhang D, Cheng R, Zhao N, Che N, Guo Y, Dong X, Zhao X
Journal of gastroenterology 2022 Oct;57(10):784-797

Regulation of Semaphorin3A in the process of cutaneous wound healing.

Zheng Y, Jiang F, Wang C, Dong M, Wang C, Yan E, Wang Y, Zhu Z, Xiong X, Ding X, Ye J, He Y, Zhang H, Zhou J, Zhang W, Wu Y, Song X
Cell death and differentiation 2022 Oct;29(10):1941-1954

FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2.

Sun M, Zhang X, Bi F, Wang D, Zhou X, Li X, Yang Q
Cancers 2022 Oct 25;14(21)

ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12.

Yun J, Kim YS, Heo MJ, Kim MJ, Moon A, Kim SG
International journal of cancer 2022 May 15;150(10):1690-1705

Long non-coding RNA small nucleolar RNA host gene 1 alleviates the progression of recurrent spontaneous abortion via the microRNA-183-5p/ZEB2 axis.

Mo Y, Chen Z, Liu X, Gong F, Huang H, Hua R, Fang Y, Liang F
Reproductive biology 2022 Mar;22(1):100611

Chelerythrine inhibits the progression of glioblastoma by suppressing the TGFB1-ERK1/2/Smad2/3-Snail/ZEB1 signaling pathway.

Zhu M, Niu J, Jiang J, Dong T, Chen Y, Yang X, Liu P
Life sciences 2022 Mar 15;293:120358

Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.

Shi YX, Sun ZW, Jia DL, Wang HB
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jul;24(7):1403-1412

Glutamine deficiency promotes recurrence and metastasis in colorectal cancer through enhancing epithelial-mesenchymal transition.

Sun H, Zhang C, Zheng Y, Liu C, Wang X, Cong X
Journal of translational medicine 2022 Jul 22;20(1):330

SPOCK1 promotes metastasis in pancreatic cancer via NF-κB-dependent epithelial-mesenchymal transition by interacting with IκB-α.

Cui X, Wang Y, Lan W, Wang S, Cui Y, Zhang X, Lin Z, Piao J
Cellular oncology (Dordrecht, Netherlands) 2022 Feb;45(1):69-84

Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses.

Lee HY, Li CC, Li WM, Hsu YL, Yeh HC, Ke HL, Yeh BW, Huang CN, Li CF, Kuo PL, Wu WJ
PeerJ 2021;9:e11343

LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process.

Sun Z, Shao B, Liu Z, Dang Q, Guo Y, Chen C, Guo Y, Chen Z, Liu J, Hu S, Yuan W, Zhou Q
Journal of Cancer 2021;12(9):2723-2734

TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.

Li R, Zhu L, Peng Y, Zhang X, Dai C, Liu D
Frontiers in oncology 2021;11:695740

Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.

Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186

PFP@PLGA/Cu(12)Sb(4)S(13)-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.

Dong T, Jiang J, Zhang H, Liu H, Zou X, Niu J, Mao Y, Zhu M, Chen X, Li Z, Chen Y, Shi C, Yang X
Nano convergence 2021 Oct 4;8(1):29

The anti-neoplastic activities of aloperine in HeLa cervical cancer cells are associated with inhibition of the IL-6-JAK1-STAT3 feedback loop.

Chen YD, Cai FY, Mao YZ, Yang YS, Xu K, Liu XF, Fan WW, Chen W, Jiang FQ, Zhang H
Chinese journal of natural medicines 2021 Nov;19(11):815-824

CircCRIM1 promotes ovarian cancer progression by working as ceRNAs of CRIM1 and targeting miR-383-5p/ZEB2 axis.

Du Y, Liu X, Zhang S, Chen S, Guan X, Li Q, Chen X, Zhao Y
Reproductive biology and endocrinology : RB&E 2021 Nov 30;19(1):176

Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.

Harn HI, Wang SP, Lai YC, Van Handel B, Liang YC, Tsai S, Schiessl IM, Sarkar A, Xi H, Hughes M, Kaemmer S, Tang MJ, Peti-Peterdi J, Pyle AD, Woolley TE, Evseenko D, Jiang TX, Chuong CM
Nature communications 2021 May 10;12(1):2595

Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis.

Liu C, Zhou X, Pan Y, Liu Y, Zhang Y
BMC cancer 2021 Jun 22;21(1):722

Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.

Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150

CircRNA Lrp6 promotes cementoblast differentiation via miR-145a-5p/Zeb2 axis.

Li M, Du M, Wang Y, Zhu J, Pan J, Cao Z, He H
Journal of periodontal research 2021 Dec;56(6):1200-1212

Cytoplasmic eIF6 promotes OSCC malignant behavior through AKT pathway.

Zhao Z, Chu W, Zheng Y, Wang C, Yang Y, Xu T, Yang X, Zhang W, Ding X, Li G, Zhang H, Zhou J, Ye J, Wu H, Song X, Wu Y
Cell communication and signaling : CCS 2021 Dec 18;19(1):121

Aging-Associated Extracellular Vesicles Contain Immune Regulatory microRNAs Alleviating Hyperinflammatory State and Immune Dysfunction in the Elderly.

Tsukamoto H, Kouwaki T, Oshiumi H
iScience 2020 Sep 25;23(9):101520

Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.

Chen Y, Niu J, Li L, Li Z, Jiang J, Zhu M, Dong T, Zhang J, Shi C, Xu P, Lu Y, Jiang Y, Liu P, Chen W
Life sciences 2020 Oct 1;258:118158

Knockdown of Linc00511 inhibits TGF-β-induced cell migration and invasion by suppressing epithelial-mesenchymal transition and down-regulating MMPs expression.

Jiang L, Xie X, Bi R, Ding F, Mei J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109049

Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.

Li X, Ma N, Zhang Y, Wei H, Zhang H, Pang X, Li X, Wu D, Wang D, Yang Z, Zhang S
Cell death & disease 2020 May 26;11(5):399

Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma.

Hu Y, Yu J, Wang Q, Zhang L, Chen X, Cao Y, Zhao J, Xu Y, Jiang D, Wang Y, Xiong W
Molecular therapy oncolytics 2020 Mar 27;16:272-288

Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway.

Liu J, Chen Y, Cao Z, Guan B, Peng J, Chen Y, Zhan Z, Sferra TJ, Sankararaman S, Lin J
The Journal of international medical research 2020 Jun;48(6):300060520925598

Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.

Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196

CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.

Zhong Q, Fang Y, Lai Q, Wang S, He C, Li A, Liu S, Yan Q
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132

Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.

Wang H, Wang C, Peng G, Yu D, Cui XG, Sun YH, Ma X
Molecular cancer research : MCR 2020 Feb;18(2):240-252

KLF5 regulates epithelial-mesenchymal transition of liver cancer cells in the context of p53 loss through miR-192 targeting of ZEB2.

Sun L, Zhou X, Li Y, Chen W, Wu S, Zhang B, Yao J, Xu A
Cell adhesion & migration 2020 Dec;14(1):182-194

Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.

Guo Y, Fan Y, Pei X
Cancer medicine 2020 Apr;9(7):2564-2578

LncRNA LINP1 confers tamoxifen resistance and negatively regulated by ER signaling in breast cancer.

Ma T, Liang Y, Li Y, Song X, Zhang N, Li X, Chen B, Zhao W, Wang L, Yang Q
Cellular signalling 2020 Apr;68:109536

Long noncoding RNA FBXL19-AS1 induces tumor growth and metastasis by sponging miR-203a-3p in lung adenocarcinoma.

Wang L, Zhang X, Liu Y, Xu S
Journal of cellular physiology 2020 Apr;235(4):3612-3625

The Lnc LINC00461/miR-30a-5p facilitates progression and malignancy in non-small cell lung cancer via regulating ZEB2.

Li X, Liu J, Liu M, Xia C, Zhao Q
Cell cycle (Georgetown, Tex.) 2020 Apr;19(7):825-836

Circular RNA hsa_circ_0000326 acts as a miR-338-3p sponge to facilitate lung adenocarcinoma progression.

Xu Y, Yu J, Huang Z, Fu B, Tao Y, Qi X, Mou Y, Hu Y, Wang Y, Cao Y, Jiang D, Xie J, Xu Y, Zhao J, Xiong W
Journal of experimental & clinical cancer research : CR 2020 Apr 5;39(1):57

Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.

Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473

HOXB8 enhances the proliferation and metastasis of colorectal cancer cells by promoting EMT via STAT3 activation.

Wang T, Lin F, Sun X, Jiang L, Mao R, Zhou S, Shang W, Bi R, Lu F, Li S
Cancer cell international 2019;19:3

LncRNA SNHG5 Promotes Proliferation of Glioma by Regulating miR-205-5p/ZEB2 Axis.

Meng X, Deng Y, Lv Z, Liu C, Guo Z, Li Y, Liu H, Xie B, Jin Z, Lin F, Zhu H
OncoTargets and therapy 2019;12:11487-11496

MicroRNA-507 represses the malignant behaviors of non-small cell lung cancer via targeting zinc finger E-box binding homeobox 2.

Lv HL, Li ZL, Song YB
European review for medical and pharmacological sciences 2019 Nov;23(22):9955-9964

SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.

Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129

Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.

Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139

Overexpression of ZEB2-AS1 promotes epithelial-to-mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma.

Diao P, Ge H, Song Y, Wu Y, Li J, Li Z, Yang J, Wang Y, Cheng J
Journal of cellular and molecular medicine 2019 Jun;23(6):4269-4280

Zinc finger E‑box binding homeobox 2 functions as an oncogene in human laryngeal squamous cell carcinoma.

Li Q, Ma L, Wu Z, Wang G, Huang Q, Shen Z, Yu R
Molecular medicine reports 2019 Jun;19(6):4545-4552

Long noncoding RNA MAGI1-IT1 promoted invasion and metastasis of epithelial ovarian cancer via the miR-200a/ZEB axis.

Gao H, Li X, Zhan G, Zhu Y, Yu J, Wang J, Li L, Wu W, Liu N, Guo X
Cell cycle (Georgetown, Tex.) 2019 Jun;18(12):1393-1406

Schisandrin B attenuates renal fibrosis via miR-30e-mediated inhibition of EMT.

Cao G, Li S, Shi H, Yin P, Chen J, Li H, Zhong Y, Diao LT, Du B
Toxicology and applied pharmacology 2019 Dec 15;385:114769

The DNA Endonuclease Mus81 Regulates ZEB1 Expression and Serves as a Target of BET4 Inhibitors in Gastric Cancer.

Yin Y, Liu W, Shen Q, Zhang P, Wang L, Tao R, Li H, Ma X, Zeng X, Cheong JH, Song S, Ajani JA, Mills GB, Tao K, Peng G
Molecular cancer therapeutics 2019 Aug;18(8):1439-1450

PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.

Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307

IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.

Wu X, Tao P, Zhou Q, Li J, Yu Z, Wang X, Li J, Li C, Yan M, Zhu Z, Liu B, Su L
Oncotarget 2017 Mar 28;8(13):20741-20750

miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition.

Yang J, Zhou CZ, Zhu R, Fan H, Liu XX, Duan XY, Tang Q, Shou ZX, Zuo DM
Journal of gastroenterology and hepatology 2017 Dec;32(12):1966-1974

Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expression.

Zhang S, Li J, Liu P, Xu J, Zhao W, Xie C, Yin Z, Wang X
Oncotarget 2015 May 10;6(13):11074-86

High levels of secreted frizzled-related protein 1 correlate with poor prognosis and promote tumourigenesis in gastric cancer.

Qu Y, Ray PS, Li J, Cai Q, Bagaria SP, Moran C, Sim MS, Zhang J, Turner RR, Zhu Z, Cui X, Liu B
European journal of cancer (Oxford, England : 1990) 2013 Nov;49(17):3718-28

No comments: Submit comment

No validations: Submit validation data