Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PB9883 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-RAB7/RAB7A Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for RAB7/RAB7A detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB, ICC/IF, FCM. Reactive species: Human;Mouse;Rat. RAB7/RAB7A information: Molecular Weight: 23490 MW; Subcellular Localization: Cytoplasmic vesicle, phagosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Late endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Lysosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Melanosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Lipid droplet . Colocalizes with OSBPL1A at the late endosome (PubMed:16176980). Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Recruited to phagosomes containing S.aureus or Mycobacterium (PubMed:21255211). Lipid droplet localization is increased upon ADRB2 stimulation (By similarity); Tissue Specificity: Widely expressed; high expression found in skeletal muscle.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Estrogen protects against acidosis-mediated articular chondrocyte injury by promoting ASIC1a protein degradation.
Autophagy protects murine macrophages from β-cypermethrin-induced mitochondrial dysfunction and cytotoxicity via the reduction of oxidation stress.
Su JW, Li SF, Tao JJ, Xu YY, Wang K, Qian XW, Deng G, Peng XQ, Chen FH
European journal of pharmacology 2021 Oct 5;908:174381
European journal of pharmacology 2021 Oct 5;908:174381
Autophagy protects murine macrophages from β-cypermethrin-induced mitochondrial dysfunction and cytotoxicity via the reduction of oxidation stress.
He B, Wang X, Zhu J, Kong B, Wei L, Jin Y, Fu Z
Environmental pollution (Barking, Essex : 1987) 2019 Jul;250:416-425
Environmental pollution (Barking, Essex : 1987) 2019 Jul;250:416-425
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Western blot analysis of RAB7 expression in rat brain extract (lane 1), mouse spleen extract (lane 2), HELA whole cell lysates (lane 3) and MCF-7 whole cell lysates (lane 4). RAB7 at 23KD was detected using rabbit anti- RAB7 Antigen Affinity purified polyclonal antibody (Catalog # PB9883) at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002).
- Additional image