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- Antibody Data
- Antigen structure
- References [94]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 55469-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55469-1-AP, RRID:AB_11182831
- Product name
- RAB7A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAB7A antibody (Cat. #55469-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Disulfidptosis-related genes signature predicts prognosis and immune microenvironment in colon cancer.
Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease.
Dynamin-2 promotes Atg9A retrieval from phagophores during autophagy.
Selective peptide-guided transcytosis enhances extracellular vesicle-mediated siRNA delivery across the blood-brain barrier.
Centrosomal P4.1-associated protein is a novel regulator of ESCRT pathway function during endosome maturation.
YY1 nitration participates in DbCM cardiomyocyte lipotoxicity by inhibiting ANXA3-induced microlipophagy.
MCL1 promotes porcine epidemic diarrhea virus replication by modulating arachidonic acid metabolic pathway.
Luteolin as a novel therapeutic for diabetic kidney disease: Targeting the ADAM10-TREM2 pathway.
A nature-inspired nanoplatform for multi-protein targeted degradation via the autophagy-lysosome pathway.
SESN2 inhibits tubular exosome secretion and diabetic kidney disease progression by restoring the autophagy‒lysosome pathway.
APT1-derived depalmitoylation of CD36 alleviates diabetes-induced lipotoxicity in podocytes.
Fenofibrate suppresses Mycoplasma bovis infection via autophagy-mediated cholesterol regulation in bovine mammary epithelial cells and murine mammary tissue.
STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation.
Activation of Rab7-mediated lipophagy is required for triptolide to induce ferroptosis in hepatic cells.
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
Activation of Lysosomal Retrograde Transport Triggers TPC1-IP3R1 Ca(2+) Crosstalk at Lysosome-ER MCSs Leading to Lethal Depleting of ER Calcium.
Centrosomal P4.1-associated protein (CPAP) is a novel regulator of ESCRT pathway function during endosome maturation.
Identification of a novel FOXO3‑associated prognostic model in hepatocellular carcinoma.
Syntaxin-6 restricts SARS-CoV-2 infection by facilitating virus trafficking to autophagosomes.
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
Methamphetamine and Methamphetamine-Induced Neuronal Exosomes Modulate the Activity of Rab7a via PTEN to Exert an Influence on the Disordered Autophagic Flux Induced in Neurons.
Induction of MASH-like pathogenesis in the Nwd1(-/-) mouse liver.
Exosomal miR-196a-5p Secreted by Bone Marrow Mesenchymal Stem Cells Inhibits Ferroptosis and Promotes Drug Resistance of Acute Myeloid Leukemia.
Cholesterol-dependent Nsp5-endosomes co-trafficking to lysosomes facilitates porcine reproductive and respiratory syndrome virus replication by activating autophagy.
PFOS causes lysosomes-regulated mitochondrial fission through TRPML1-VDAC1 and oligomerization of MCU/ATP5J2.
ATP7A Maintains Bactericidal Function of Neutrophils and Macrophages via Regulating the Formation and Activation of Phagolysosomes.
GORASP2 promotes phagophore closure and autophagosome maturation into autolysosomes.
Polymeric Polylactic Acid-Glycolic Acid-Based Nanoparticles Deliver Nintedanib Across the Blood-Brain Barrier to Inhibit Glioblastoma Growth.
PI3K/mTOR Inhibitor Induces Context-Dependent Apoptosis and Methuosis in Cancer Cells.
Endolysosomal channel TMEM175 mediates antitoxin activity of DABMA.
Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice.
The different roles of V-ATPase a subunits in phagocytosis/endocytosis and autophagy.
Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7.
Nerve Growth Factor Signaling Modulates the Expression of Glutaminase in Dorsal Root Ganglion Neurons during Peripheral Inflammation.
Downregulation of MYBL1 in endothelial cells contributes to atherosclerosis by repressing PLEKHM1-inducing autophagy.
Collapse of late endosomal pH elicits a rapid Rab7 response via the V-ATPase and RILP.
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
Cell death induced by nicotine in human neuroblastoma SH-SY5Y cells is mainly attributed to cytoplasmic vacuolation originating from the trans-Golgi network.
SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.
RAB22A sorts epithelial growth factor receptor (EGFR) from early endosomes to recycling endosomes for microvesicles release.
CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A.
Loss of SARM1 ameliorates secondary thalamic neurodegeneration after cerebral infarction.
Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.
Atg5-deficient mesenchymal stem cells protect against non-alcoholic fatty liver by accelerating hepatocyte growth factor secretion.
Subcellular localization of viral proteins after porcine epidemic diarrhea virus infection and their roles in the viral life cycle.
The Prognostic Biomarker RAB7A Promotes Growth and Metastasis of Liver Cancer Cells by Regulating Glycolysis and YAP1 Activation.
RILP Induces Cholesterol Accumulation in Lysosomes by Inhibiting Endoplasmic Reticulum-Endolysosome Interactions.
Absence of motor impairments or pathological changes in TMEM230 knockout rats.
Common Markers and Small Molecule Inhibitors in Golgi Studies.
Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.
Emodin and rhapontigenin inhibit the replication of African swine fever virus by interfering with virus entry.
EGFR-T790M Mutation-Derived Interactome Rerouted EGFR Translocation Contributing to Gefitinib Resistance in Non-Small Cell Lung Cancer.
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy.
C9orf72-catalyzed GTP loading of Rab39A enables HOPS-mediated membrane tethering and fusion in mammalian autophagy.
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers.
25-hydroxycholesterol inhibits classical swine fever virus entry into porcine alveolar macrophages by depleting plasma membrane cholesterol.
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma.
Leucine-rich repeat kinase 2 (LRRK2) inhibition upregulates microtubule-associated protein 1B to ameliorate lysosomal dysfunction and parkinsonism.
Porcine Enteric Alphacoronavirus Entry through Multiple Pathways (Caveolae, Clathrin, and Macropinocytosis) Requires Rab GTPases for Endosomal Transport.
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
High RAS-related protein Rab-7a (RAB7A) expression is a poor prognostic factor in pancreatic adenocarcinoma.
Cholesterol determines the cytosolic entry and seeded aggregation of tau.
Bile acids promote the caveolae-associated entry of swine acute diarrhea syndrome coronavirus in porcine intestinal enteroids.
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Vps34 Inhibits Hepatocellular Carcinoma Invasion by Regulating Endosome-Lysosome Trafficking via Rab7-RILP and Rab11.
SorCS3 promotes the internalization of p75(NTR) to inhibit GBM progression.
The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction.
Downregulation of RAB7 and Caveolin-1 increases MMP-2 activity in renal tubular epithelial cells under hypoxic conditions.
Porcine Circovirus Type 3 Enters Into PK15 Cells Through Clathrin- and Dynamin-2-Mediated Endocytosis in a Rab5/Rab7 and pH-Dependent Fashion.
Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218.
Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis.
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Methionine-chelated Zn promotes anabolism by integrating mTOR signal and autophagy pathway in juvenile yellow catfish.
Potential application of human neural crest-derived nasal turbinate stem cells for the treatment of neuropathology and impaired cognition in models of Alzheimer's disease.
FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation.
RAB31 marks and controls an ESCRT-independent exosome pathway.
Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.
Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation.
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway.
The N-glycosylation of Equine Tetherin Affects Antiviral Activity by Regulating Its Subcellular Localization.
An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice.
CHML promotes liver cancer metastasis by facilitating Rab14 recycle.
Palmitoylome profiling indicates that androgens regulate the palmitoylation of α‑tubulin in prostate cancer‑derived LNCaP cells and supernatants.
Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation.
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity.
Hepatitis B virus X protein is capable of down-regulating protein level of host antiviral protein APOBEC3G.
Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway.
Synergism between upregulation of Rab7 and inhibition of autophagic degradation caused by mycoplasma facilitates intracellular mycoplasma infection.
Jiang W, Yang H, Li R, Li Y, Xia S
Frontiers in molecular biosciences 2026;13:1756041
Frontiers in molecular biosciences 2026;13:1756041
Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease.
Zhao J, Zou J, Zhou C, Wang Y, Liu Y, Zhou Y, Wang Y, Zhang X, Yang H, Yin H, Bai D, Zhao Y, Lu N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e21681
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e21681
Dynamin-2 promotes Atg9A retrieval from phagophores during autophagy.
Caliri A, Riera AM, Saha A, Kolitsida P, Martinez CI, Itskanov S, Steffen J, Koehler CM, van der Bliek AM
bioRxiv : the preprint server for biology 2026 Mar 13;
bioRxiv : the preprint server for biology 2026 Mar 13;
Selective peptide-guided transcytosis enhances extracellular vesicle-mediated siRNA delivery across the blood-brain barrier.
Fang J, Zhang L, Wang Y, Chen M, He Y, Zhang CY, Zhang Y, Jiang X, Li J
The Journal of biological chemistry 2026 Jan;302(1):110942
The Journal of biological chemistry 2026 Jan;302(1):110942
Centrosomal P4.1-associated protein is a novel regulator of ESCRT pathway function during endosome maturation.
Gudi R, Vasu C
iScience 2026 Feb 20;29(2):114659
iScience 2026 Feb 20;29(2):114659
YY1 nitration participates in DbCM cardiomyocyte lipotoxicity by inhibiting ANXA3-induced microlipophagy.
Chai J, Han L, Mo D, Bai Y, Yang Y, Ding Y, Chen S, Kong X, Zhu X, Xu L, Dai H, Wang W
Redox biology 2026 Apr;91:104085
Redox biology 2026 Apr;91:104085
MCL1 promotes porcine epidemic diarrhea virus replication by modulating arachidonic acid metabolic pathway.
Shang H, Yang S, Sun M, Zhao Y, Guo R, Wang W, Qian B, Li Y, Hu M, Bian X, Cao Q, Li C, Fan B, Li B
PLoS pathogens 2026 Apr;22(4):e1014170
PLoS pathogens 2026 Apr;22(4):e1014170
Luteolin as a novel therapeutic for diabetic kidney disease: Targeting the ADAM10-TREM2 pathway.
Deng L, Wang Y, Shi C, Wu J, Yao J, Shen W, Zhang Z, Liu R, Wang X, Zhu H, Zhang L, Cai G, Zhou J, Hong Q, Chen X
Journal of advanced research 2026 Apr 24;
Journal of advanced research 2026 Apr 24;
A nature-inspired nanoplatform for multi-protein targeted degradation via the autophagy-lysosome pathway.
Tong B, Wang Y, Wei J, Ou Z, Liang H, Lei J, Zhu D, Xu H, Tan L, Liao Z, Yang C
Cell chemical biology 2026 Apr 16;33(4):523-537.e7
Cell chemical biology 2026 Apr 16;33(4):523-537.e7
SESN2 inhibits tubular exosome secretion and diabetic kidney disease progression by restoring the autophagy‒lysosome pathway.
Zheng Z, Chen J, Xue X, Ma X, Zhang S, Wang M, Xue Y, Jia Y
International journal of biological sciences 2025;21(9):4215-4230
International journal of biological sciences 2025;21(9):4215-4230
APT1-derived depalmitoylation of CD36 alleviates diabetes-induced lipotoxicity in podocytes.
Wang J, Hu J, Hu H, Guan Q, Zhu Z, Yang Q, Ding G
International journal of biological sciences 2025;21(9):3852-3866
International journal of biological sciences 2025;21(9):3852-3866
Fenofibrate suppresses Mycoplasma bovis infection via autophagy-mediated cholesterol regulation in bovine mammary epithelial cells and murine mammary tissue.
Xu M, Wang T, Deng X, Liu Y, Zhu Z, Barkema HW, Cobo ER, Kastelic JP, Zhou X, Han B
Frontiers in cellular and infection microbiology 2025;15:1731492
Frontiers in cellular and infection microbiology 2025;15:1731492
STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation.
Huang Y, Xu F, Wang L, Mei S, Zhao F, Wang L, Xie Y, Wei L, Hu Y, Gao Z, Xue T, Fang J, Guo F
EMBO reports 2025 Sep;26(18):4607-4630
EMBO reports 2025 Sep;26(18):4607-4630
Activation of Rab7-mediated lipophagy is required for triptolide to induce ferroptosis in hepatic cells.
Liu S, Su Y, Han B, Yin L, Li H, Wang Y, Zhou K, Li P, Wei Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115568
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115568
USP47 Regulates Excitatory Synaptic Plasticity and Modulates Seizures in Murine Models by Blocking Ubiquitinated AMPAR Degradation.
Yang J, Zhang H, Wang Y, Luo Y, Zheng W, Liu Y, Jiang Q, Deng J, Liu Q, Zhang P, Huang H, Yu C, Xu Z, Chen Y
Neuroscience bulletin 2025 Oct;41(10):1805-1823
Neuroscience bulletin 2025 Oct;41(10):1805-1823
Activation of Lysosomal Retrograde Transport Triggers TPC1-IP3R1 Ca(2+) Crosstalk at Lysosome-ER MCSs Leading to Lethal Depleting of ER Calcium.
Zhu MY, Guo YJ, Zhu YQ, Wang HZ, Wang HD, Chen HY, Jiang YX, Li H, Hui H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e15313
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e15313
Centrosomal P4.1-associated protein (CPAP) is a novel regulator of ESCRT pathway function during endosome maturation.
Gudi R, Vasu C
bioRxiv : the preprint server for biology 2025 Nov 26;
bioRxiv : the preprint server for biology 2025 Nov 26;
Identification of a novel FOXO3‑associated prognostic model in hepatocellular carcinoma.
Guan S, Lin Q, Huang P, Lin K, Duan S
Oncology letters 2025 May;29(5):230
Oncology letters 2025 May;29(5):230
Syntaxin-6 restricts SARS-CoV-2 infection by facilitating virus trafficking to autophagosomes.
Sun H, Yang Q, Zhang Y, Cui S, Zhou Z, Zhang P, Jia L, Zhang M, Wang Y, Chen X, Pei R
Journal of virology 2025 May 20;99(5):e0000225
Journal of virology 2025 May 20;99(5):e0000225
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
Zhang S, Gu M, Yin H, Pan S, Xie H, Chen W, Gul S, Zhao Y, Wang Z, Zheng W, You Y, You B
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
Methamphetamine and Methamphetamine-Induced Neuronal Exosomes Modulate the Activity of Rab7a via PTEN to Exert an Influence on the Disordered Autophagic Flux Induced in Neurons.
Qiu H, Zhang M, Li M, Chen C, Wang H, Yue X
International journal of molecular sciences 2025 Mar 14;26(6)
International journal of molecular sciences 2025 Mar 14;26(6)
Induction of MASH-like pathogenesis in the Nwd1(-/-) mouse liver.
Yamada S, Ogawa H, Funato M, Kato M, Nakadate K, Mizukoshi T, Kawakami K, Kobayashi R, Horii T, Hatada I, Sakakibara SI
Communications biology 2025 Mar 11;8(1):348
Communications biology 2025 Mar 11;8(1):348
Exosomal miR-196a-5p Secreted by Bone Marrow Mesenchymal Stem Cells Inhibits Ferroptosis and Promotes Drug Resistance of Acute Myeloid Leukemia.
Fan B, Wang L, Hu T, Zheng L, Wang J
Antioxidants & redox signaling 2025 Jun;42(16-18):933-953
Antioxidants & redox signaling 2025 Jun;42(16-18):933-953
Cholesterol-dependent Nsp5-endosomes co-trafficking to lysosomes facilitates porcine reproductive and respiratory syndrome virus replication by activating autophagy.
Dong H, Pei Q, Ren J, Zhang Y, Wei X, Shen A, Lu Y, Zhang Z, Du Y, Zhuang G, Zhang A, Duan H
Veterinary microbiology 2025 Jun;305:110507
Veterinary microbiology 2025 Jun;305:110507
PFOS causes lysosomes-regulated mitochondrial fission through TRPML1-VDAC1 and oligomerization of MCU/ATP5J2.
Yang W, Li Y, Feng R, Liang P, Tian K, Hu L, Wang K, Qiu T, Zhang J, Sun X, Yao X
Journal of hazardous materials 2025 Jun 5;489:137685
Journal of hazardous materials 2025 Jun 5;489:137685
ATP7A Maintains Bactericidal Function of Neutrophils and Macrophages via Regulating the Formation and Activation of Phagolysosomes.
Jing Y, Shi J, Xie Z, Shen Z, Zhang J, Wang F, Li K, Su J, Liu JX
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70661
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 15;39(11):e70661
GORASP2 promotes phagophore closure and autophagosome maturation into autolysosomes.
Xing Y, Huang L, Jian Y, Zhang Z, Zhao X, Zhang X, Fu T, Zhang Y, Wang Y, Zhang X
Autophagy 2025 Jan;21(1):37-53
Autophagy 2025 Jan;21(1):37-53
Polymeric Polylactic Acid-Glycolic Acid-Based Nanoparticles Deliver Nintedanib Across the Blood-Brain Barrier to Inhibit Glioblastoma Growth.
Dang Y, Zhao Z, Wang B, Du A, Li S, Yuan G, Pan Y
International journal of molecular sciences 2025 Jan 7;26(2)
International journal of molecular sciences 2025 Jan 7;26(2)
PI3K/mTOR Inhibitor Induces Context-Dependent Apoptosis and Methuosis in Cancer Cells.
Hua X, Chen P, Zeng W, Han Y, Guo Y, Chen Y, Li C, Du Y, Ma M, Dong S
Pharmaceuticals (Basel, Switzerland) 2025 Dec 4;18(12)
Pharmaceuticals (Basel, Switzerland) 2025 Dec 4;18(12)
Endolysosomal channel TMEM175 mediates antitoxin activity of DABMA.
Wu Y, Huang J, Zhang F, Guivel-Benhassine F, Hubert M, Schwartz O, Xiao W, Cintrat JC, Qu L, Barbier J, Gillet D, Cang C
The FEBS journal 2024 Sep;291(18):4142-4154
The FEBS journal 2024 Sep;291(18):4142-4154
Sortilin-mediated translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice.
Yang M, Ge J, Liu YL, Wang HY, Wang ZH, Li DP, He R, Xie YY, Deng HY, Peng XM, Wang WS, Liu JD, Zhu ZZ, Yu XF, Maretich P, Kajimura S, Pan RP, Chen Y
Nature communications 2024 Sep 5;15(1):7746
Nature communications 2024 Sep 5;15(1):7746
The different roles of V-ATPase a subunits in phagocytosis/endocytosis and autophagy.
Chen Q, Kou H, Demy DL, Liu W, Li J, Wen Z, Herbomel P, Huang Z, Zhang W, Xu J
Autophagy 2024 Oct;20(10):2297-2313
Autophagy 2024 Oct;20(10):2297-2313
Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7.
Li C, Fu J, Shao S, Luo ZQ
PLoS pathogens 2024 May;20(5):e1011783
PLoS pathogens 2024 May;20(5):e1011783
Nerve Growth Factor Signaling Modulates the Expression of Glutaminase in Dorsal Root Ganglion Neurons during Peripheral Inflammation.
Gujar V, Pande RD, Hardas BM, Das S
International journal of molecular sciences 2024 May 31;25(11)
International journal of molecular sciences 2024 May 31;25(11)
Downregulation of MYBL1 in endothelial cells contributes to atherosclerosis by repressing PLEKHM1-inducing autophagy.
Ding SA, Liu H, Zheng R, Ge Y, Fu Z, Mei J, Tang M
Cell biology and toxicology 2024 May 27;40(1):40
Cell biology and toxicology 2024 May 27;40(1):40
Collapse of late endosomal pH elicits a rapid Rab7 response via the V-ATPase and RILP.
Mulligan RJ, Magaj MM, Digilio L, Redemann S, Yap CC, Winckler B
Journal of cell science 2024 May 1;137(9)
Journal of cell science 2024 May 1;137(9)
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
Chen X, Liang Y, Weng Z, Hu C, Peng Y, Sun Y, Gao Q, Huang Z, Tang S, Gong L, Zhang G
PLoS pathogens 2024 Mar;20(3):e1012103
PLoS pathogens 2024 Mar;20(3):e1012103
Cell death induced by nicotine in human neuroblastoma SH-SY5Y cells is mainly attributed to cytoplasmic vacuolation originating from the trans-Golgi network.
Li J, Wang H, Chen H, Li X, Liu Y, Hou H, Hu Q
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114431
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114431
SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.
Zhang J, Kennedy A, de Melo Jorge DM, Xing L, Reid W, Bui S, Joppich J, Rose M, Ercan S, Tang Q, Tai AW, Wang Y
bioRxiv : the preprint server for biology 2024 Mar 15;
bioRxiv : the preprint server for biology 2024 Mar 15;
RAB22A sorts epithelial growth factor receptor (EGFR) from early endosomes to recycling endosomes for microvesicles release.
Lin Y, Wei D, He X, Huo L, Wang J, Zhang X, Wu Y, Zhang R, Gao Y, Kang T
Journal of extracellular vesicles 2024 Jul;13(7):e12494
Journal of extracellular vesicles 2024 Jul;13(7):e12494
CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A.
Guo F, Du N, Wen X, Li Z, Guo Y, Zhou L, Hoffman AR, Li L, Hu JF, Cui J
Cellular and molecular life sciences : CMLS 2024 Jul 24;81(1):307
Cellular and molecular life sciences : CMLS 2024 Jul 24;81(1):307
Loss of SARM1 ameliorates secondary thalamic neurodegeneration after cerebral infarction.
Zhou K, Tan Y, Zhang G, Li J, Xing S, Chen X, Wen J, Li G, Fan Y, Zeng J, Zhang J
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Feb;44(2):224-238
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Feb;44(2):224-238
Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.
Mulligan RJ, Magaj MM, Digilio L, Redemann S, Yap CC, Winckler B
bioRxiv : the preprint server for biology 2024 Feb 17;
bioRxiv : the preprint server for biology 2024 Feb 17;
Atg5-deficient mesenchymal stem cells protect against non-alcoholic fatty liver by accelerating hepatocyte growth factor secretion.
Zhang C, Ji J, Du X, Zhang L, Song Y, Wang Y, Jiang Y, Li K, Chang T
Cell communication and signaling : CCS 2024 Dec 3;22(1):579
Cell communication and signaling : CCS 2024 Dec 3;22(1):579
Subcellular localization of viral proteins after porcine epidemic diarrhea virus infection and their roles in the viral life cycle.
Chen XN, Cai ST, Liang YF, Weng ZJ, Song TQ, Li X, Sun YS, Peng YZ, Huang Z, Gao Q, Tang SQ, Zhang GH, Gong L
International journal of biological macromolecules 2024 Aug;274(Pt 2):133401
International journal of biological macromolecules 2024 Aug;274(Pt 2):133401
The Prognostic Biomarker RAB7A Promotes Growth and Metastasis of Liver Cancer Cells by Regulating Glycolysis and YAP1 Activation.
Zhang JY, Zhu X, Liu Y, Wu X
Journal of cellular biochemistry 2024 Aug;125(8):e30621
Journal of cellular biochemistry 2024 Aug;125(8):e30621
RILP Induces Cholesterol Accumulation in Lysosomes by Inhibiting Endoplasmic Reticulum-Endolysosome Interactions.
Han Y, Liu X, Xu L, Wei Z, Gu Y, Ren Y, Hua W, Zhang Y, Liu X, Jiang C, Zhuang R, Hong W, Wang T
Cells 2024 Aug 6;13(16)
Cells 2024 Aug 6;13(16)
Absence of motor impairments or pathological changes in TMEM230 knockout rats.
Zhang W, Peng H, Yang D, Song G, He J, Zhou Y, Huang C, Huang B
Neuroscience letters 2024 Aug 10;837:137921
Neuroscience letters 2024 Aug 10;837:137921
Common Markers and Small Molecule Inhibitors in Golgi Studies.
Bui S, Stark D, Li J, Zhang J, Wang Y
Methods in molecular biology (Clifton, N.J.) 2023;2557:453-493
Methods in molecular biology (Clifton, N.J.) 2023;2557:453-493
Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.
Arab M, Nayak SC, Vitali T, Lowe M
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111
Emodin and rhapontigenin inhibit the replication of African swine fever virus by interfering with virus entry.
Guo Y, Chen Y, Wang Q, Wang Z, Gong L, Sun Y, Song Z, Chang H, Zhang G, Wang H
Veterinary microbiology 2023 Sep;284:109794
Veterinary microbiology 2023 Sep;284:109794
EGFR-T790M Mutation-Derived Interactome Rerouted EGFR Translocation Contributing to Gefitinib Resistance in Non-Small Cell Lung Cancer.
Wu PS, Lin MH, Hsiao JC, Lin PY, Pan SH, Chen YJ
Molecular & cellular proteomics : MCP 2023 Sep;22(9):100624
Molecular & cellular proteomics : MCP 2023 Sep;22(9):100624
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy.
Sun Y, Zheng H, Qian L, Liu Y, Zhu D, Xu Z, Chang W, Xu J, Wang L, Sun B, Gu L, Yuan H, Lou H
JACS Au 2023 Oct 23;3(10):2749-2762
JACS Au 2023 Oct 23;3(10):2749-2762
C9orf72-catalyzed GTP loading of Rab39A enables HOPS-mediated membrane tethering and fusion in mammalian autophagy.
Zhang S, Tong M, Zheng D, Huang H, Li L, Ungermann C, Pan Y, Luo H, Lei M, Tang Z, Fu W, Chen S, Liu X, Zhong Q
Nature communications 2023 Oct 11;14(1):6360
Nature communications 2023 Oct 11;14(1):6360
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers.
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Immunity 2023 Nov 14;56(11):2570-2583.e6
Immunity 2023 Nov 14;56(11):2570-2583.e6
25-hydroxycholesterol inhibits classical swine fever virus entry into porcine alveolar macrophages by depleting plasma membrane cholesterol.
Zhang L, Yi Y, Wang T, Song M, Guo K, Zhang Y
Veterinary microbiology 2023 Mar;278:109668
Veterinary microbiology 2023 Mar;278:109668
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Zheng W, Chen Q, Liu H, Zeng L, Zhou Y, Liu X, Bai Y, Zhang J, Pan Y, Shao C
Autophagy 2023 Mar;19(3):839-857
Autophagy 2023 Mar;19(3):839-857
The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma.
Niu J, Yan T, Guo W, Wang W, Ren T, Huang Y, Zhao Z, Yu Y, Chen C, Huang Q, Lou J, Guo L
Autophagy 2023 Jun;19(6):1693-1710
Autophagy 2023 Jun;19(6):1693-1710
Leucine-rich repeat kinase 2 (LRRK2) inhibition upregulates microtubule-associated protein 1B to ameliorate lysosomal dysfunction and parkinsonism.
Chen K, Tang F, Du B, Yue ZZ, Jiao LL, Ding XL, Tuo QZ, Meng J, He SY, Dai L, Lei P, Wei XW
MedComm 2023 Dec;4(6):e429
MedComm 2023 Dec;4(6):e429
Porcine Enteric Alphacoronavirus Entry through Multiple Pathways (Caveolae, Clathrin, and Macropinocytosis) Requires Rab GTPases for Endosomal Transport.
Chen XN, Liang YF, Weng ZJ, Quan WP, Hu C, Peng YZ, Sun YS, Gao Q, Huang Z, Zhang GH, Gong L
Journal of virology 2023 Apr 27;97(4):e0021023
Journal of virology 2023 Apr 27;97(4):e0021023
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
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Scientific reports 2022 Oct 19;12(1):17492
Scientific reports 2022 Oct 19;12(1):17492
Cholesterol determines the cytosolic entry and seeded aggregation of tau.
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Cell reports 2022 May 3;39(5):110776
Cell reports 2022 May 3;39(5):110776
Bile acids promote the caveolae-associated entry of swine acute diarrhea syndrome coronavirus in porcine intestinal enteroids.
Yang QY, Yang YL, Tang YX, Qin P, Wang G, Xie JY, Chen SX, Ding C, Huang YW, Zhu SJ
PLoS pathogens 2022 Jun;18(6):e1010620
PLoS pathogens 2022 Jun;18(6):e1010620
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
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Autophagy 2022 Jul;18(7):1599-1612
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Vps34 Inhibits Hepatocellular Carcinoma Invasion by Regulating Endosome-Lysosome Trafficking via Rab7-RILP and Rab11.
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Cancer research and treatment 2022 Jan;54(1):182-198
Cancer research and treatment 2022 Jan;54(1):182-198
SorCS3 promotes the internalization of p75(NTR) to inhibit GBM progression.
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Cell death & disease 2022 Apr 7;13(4):313
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The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction.
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Frontiers in cell and developmental biology 2021;9:706768
Frontiers in cell and developmental biology 2021;9:706768
Downregulation of RAB7 and Caveolin-1 increases MMP-2 activity in renal tubular epithelial cells under hypoxic conditions.
Yu W, Ke X, Li M, Ye P, Peng J, Li H
Open medicine (Warsaw, Poland) 2021;16(1):1428-1437
Open medicine (Warsaw, Poland) 2021;16(1):1428-1437
Porcine Circovirus Type 3 Enters Into PK15 Cells Through Clathrin- and Dynamin-2-Mediated Endocytosis in a Rab5/Rab7 and pH-Dependent Fashion.
Shi R, Hou L, Wei L, Quan R, Zhou B, Jiang H, Wang J, Zhu S, Song J, Wang D, Liu J
Frontiers in microbiology 2021;12:636307
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Acta pharmaceutica Sinica. B 2021 Oct;11(10):3178-3192
Acta pharmaceutica Sinica. B 2021 Oct;11(10):3178-3192
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Aging 2021 Oct 25;13(20):23769-23779
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Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Wang S, Xu X, Che D, Fan R, Gao M, Cao Y, Ge C, Feng Y, Li J, Xie S, Wang C, Dai F, Gao L, Wang Y
International journal of molecular sciences 2021 Oct 12;22(20)
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Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126732
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126732
Potential application of human neural crest-derived nasal turbinate stem cells for the treatment of neuropathology and impaired cognition in models of Alzheimer's disease.
Lim JY, In Park S, Park SA, Jeon JH, Jung HY, Yon JM, Jeun SS, Lim HK, Kim SW
Stem cell research & therapy 2021 Jul 13;12(1):402
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Cell death & disease 2021 Jan 13;12(1):80
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Cell research 2021 Feb;31(2):157-177
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Biochemical and biophysical research communications 2021 Apr 23;550:15-21
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Molecular medicine reports 2020 Sep;22(3):2373-2385
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Molecular medicine reports 2014 Mar;9(3):793-800
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 55469-1-AP(RAB7A antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RAB7A antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human RAB7A. This antibody recognizes human,mouse,rat antigen. The RAB7A antibody has been validated for the following applications: ELISA, WB, IHC analysis.
