NBP1-84190
antibody from Novus Biologicals
Targeting: SYNE2
DKFZP434H2235, KIAA1011, Nesp2, Nesprin-2, NUA, NUANCE, SYNE-2
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [10]
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- Product number
- NBP1-84190 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-84190, RRID:AB_11012967
- Product name
- Rabbit Polyclonal Nesprin 2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Nesprin 2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Disruption of valosin-containing protein activity causes cardiomyopathy and reveals pleiotropic functions in cardiac homeostasis.
Super-resolution microscopy reveals LINC complex recruitment at nuclear indentation sites.
Brody MJ, Vanhoutte D, Bakshi CV, Liu R, Correll RN, Sargent MA, Molkentin JD
The Journal of biological chemistry 2019 May 31;294(22):8918-8929
The Journal of biological chemistry 2019 May 31;294(22):8918-8929
Super-resolution microscopy reveals LINC complex recruitment at nuclear indentation sites.
Versaevel M, Braquenier JB, Riaz M, Grevesse T, Lantoine J, Gabriele S
Scientific reports 2014 Dec 8;4:7362
Scientific reports 2014 Dec 8;4:7362
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human kidney shows strong nuclear membrane positivity in cells in tubules.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human testis.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human kidney.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human colon.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human cerebral cortex.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human cerebral cortex shows no positivity in neurons as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human cerebral cortex, kidney, skin and testis using Anti-SYNE2 antibody NBP1-84190 (A) shows similar protein distribution across tissues to independent antibody NBP2-38620 (B).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human kidney shows moderate to strong positivity in nuclear membrane in cells in tubules.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human skin shows moderate positivity in nuclear membrane in squamous epithelial cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Nesprin 2 Antibody [NBP1-84190] - Staining of human testis shows moderate membranous positivity in cells in seminiferous ducts.