Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 10271-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10271-1-AP, RRID:AB_2100774
- Product name
- FAF1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FAF1 antibody (Cat. #10271-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The p97-UBXN1 complex regulates aggresome formation.
MiR-26a-5p Serves as an Oncogenic MicroRNA in Non-Small Cell Lung Cancer by Targeting FAF1.
FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration.
Fas-associated factor 1 promotes in neurofibrillary tangle-mediated cell death of basal forebrain cholinergic neurons in P301L transgenic mice.
Accumulation of the parkin substrate, FAF1, plays a key role in the dopaminergic neurodegeneration.
Fas-associated factor 1 as a regulator of olfactory axon guidance.
Mukkavalli S, Klickstein JA, Ortiz B, Juo P, Raman M
Journal of cell science 2021 Apr 1;134(7)
Journal of cell science 2021 Apr 1;134(7)
MiR-26a-5p Serves as an Oncogenic MicroRNA in Non-Small Cell Lung Cancer by Targeting FAF1.
Ye MF, Lin D, Li WJ, Xu HP, Zhang J
Cancer management and research 2020;12:7131-7142
Cancer management and research 2020;12:7131-7142
FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration.
Yu C, Kim BS, Kim E
Cell death and differentiation 2016 Nov 1;23(11):1873-1885
Cell death and differentiation 2016 Nov 1;23(11):1873-1885
Fas-associated factor 1 promotes in neurofibrillary tangle-mediated cell death of basal forebrain cholinergic neurons in P301L transgenic mice.
Kim JM, Kim SS, Lee YD
Neuroreport 2015 Sep 9;26(13):767-72
Neuroreport 2015 Sep 9;26(13):767-72
Accumulation of the parkin substrate, FAF1, plays a key role in the dopaminergic neurodegeneration.
Sul JW, Park MY, Shin J, Kim YR, Yoo SE, Kong YY, Kwon KS, Lee YH, Kim E
Human molecular genetics 2013 Apr 15;22(8):1558-73
Human molecular genetics 2013 Apr 15;22(8):1558-73
Fas-associated factor 1 as a regulator of olfactory axon guidance.
Cheng K, Bai L, Belluscio L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 17;31(33):11905-13
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 17;31(33):11905-13
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10271-1-AP(FAF1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 10271-1-AP(FAF1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FAF1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FAF1. This antibody recognizes human,mouse,rat antigen. The FAF1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.