Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- ABIN499818 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Fas (TNFRSF6) Associated Factor 1 (FAF1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- FAF1 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human FAF1. (AP30327CP-N)
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references Platelet hyperactivity and risk of recurrent thrombosis.
Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1.
Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB.
Apoptosis induced by human Fas-associated factor 1, hFAF1, requires its ubiquitin homologous domain, but not the Fas-binding domain.
A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis.
Harrison P, Keeling D
Journal of thrombosis and haemostasis : JTH 2006 Dec;4(12):2544-6
Journal of thrombosis and haemostasis : JTH 2006 Dec;4(12):2544-6
Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1.
Kinoshita T, Kondoh C, Hasegawa M, Imamura R, Suda T
International immunology 2006 Dec;18(12):1701-6
International immunology 2006 Dec;18(12):1701-6
Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB.
Park MY, Jang HD, Lee SY, Lee KJ, Kim E
The Journal of biological chemistry 2004 Jan 23;279(4):2544-9
The Journal of biological chemistry 2004 Jan 23;279(4):2544-9
Apoptosis induced by human Fas-associated factor 1, hFAF1, requires its ubiquitin homologous domain, but not the Fas-binding domain.
Ryu SW, Kim E
Biochemical and biophysical research communications 2001 Sep 7;286(5):1027-32
Biochemical and biophysical research communications 2001 Sep 7;286(5):1027-32
A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis.
Chu K, Niu X, Williams LT
Proceedings of the National Academy of Sciences of the United States of America 1995 Dec 5;92(25):11894-8
Proceedings of the National Academy of Sciences of the United States of America 1995 Dec 5;92(25):11894-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of FAF1 in Jurkat cell lysate with AP30327PU-N FAF1 antibody at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of FAF1 in rat spleen tissue with AP30327PU-N FAF1 antibody at 2.5 ?g/ml.