ABCC5

gene product
EST277145, MOAT-C, MRP5, SMRP
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
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389 antibodies from 34 providers.

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antibodies-online
130 antibodies
GeneTex
4 antibodies
Novus Biologicals
29 antibodies
OriGene
25 antibodies
Aviva Systems Biology
2 antibodies
Biorbyt
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Abgent
2 antibodies
LifeSpan BioSciences, Inc.
59 antibodies
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
3 antibodies
Acris Antibodies GmbH
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Abnova Corporation
5 antibodies
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
Invitrogen Antibodies
8 antibodies
Arigo
2 antibodies
Enzo Life Sciences
2 antibodies
ProSci
2 antibodies
Bioworld Technology, Inc
1 antibody
St John's Laboratory
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Diagnostics
3 antibodies
Atlas Antibodies
2 antibodies
Creative Biolabs
11 antibodies
MyBioSource
4 antibodies
GenWay
4 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
37 antibodies
Sigma-Aldrich
3 antibodies
Leading Biology
2 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody