Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 11674-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11674-1-AP, RRID:AB_2161631
- Product name
- PDLIM1/CLP36 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PDLIM1/CLP36 antibody (Cat. #11674-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Angiogenesis-Informed Preoperative CT Radiogenomics Predicts Overall Survival in Clear Cell Renal Cell Carcinoma: Development and External Validation.
ACTN2, regulated by PRDM9, affects the growth and inflammation of vascular smooth muscle cells by interacting with PDLIM1 in intracranial aneurysms.
Bridging aging, immunity, and atherosclerosis: novel insights into senescence-related genes.
Characterization of protein lactylation in healthy and ischemic mouse hearts.
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
Integrated bioinformatic analysis of immune infiltration and disulfidptosis related gene subgroups in type A aortic dissection.
Decreased PDLIM1 expression in endothelial cells contributes to the development of intracranial aneurysm.
Identification and validation of differentially expressed disulfidptosis-related genes in hypertrophic cardiomyopathy.
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
Autophagy regulates spermatid differentiation via degradation of PDLIM1.
Autophagy is required for ectoplasmic specialization assembly in sertoli cells.
Autophagy protects cardiomyocytes from the myocardial ischaemia-reperfusion injury through the clearance of CLP36.
CLP36 and RIL recruit α-actinin-1 to stress fibers and differentially regulate stress fiber dynamics in F2408 fibroblasts.
CLP36 interacts with palladin in dorsal root ganglion neurons.
Zheng Y, Du Y, Ma Z, Luo Y, Lu J, Shang P
Cancers 2026 Feb 27;18(5)
Cancers 2026 Feb 27;18(5)
ACTN2, regulated by PRDM9, affects the growth and inflammation of vascular smooth muscle cells by interacting with PDLIM1 in intracranial aneurysms.
Zhang G, Zhao J, Yu Z, Liu H
Frontiers in molecular neuroscience 2025;18:1606973
Frontiers in molecular neuroscience 2025;18:1606973
Bridging aging, immunity, and atherosclerosis: novel insights into senescence-related genes.
Lu Y, Yuan R, Xin Q, Chen K, Cong W
Frontiers in immunology 2025;16:1557266
Frontiers in immunology 2025;16:1557266
Characterization of protein lactylation in healthy and ischemic mouse hearts.
Wu D, Tang Y, Li X, Xiong S, Zhang Z, Fu J
Frontiers in cardiovascular medicine 2025;12:1644886
Frontiers in cardiovascular medicine 2025;12:1644886
Botulinum toxin type A inhibits microglia pyroptosis by suppressing Cblb-mediated degradation of Pdlim1 to attenuate neuropathic pain.
Tian S, Wu L, Zheng H, Cheng Z, Liu J, Liu M, Yu X, Tu J, Wu W
The journal of headache and pain 2025 Jul 22;26(1):165
The journal of headache and pain 2025 Jul 22;26(1):165
Integrated bioinformatic analysis of immune infiltration and disulfidptosis related gene subgroups in type A aortic dissection.
Wang D, Wang C, Liu H, Zhang Z, Li M, Ge X, Bi A, Gao C, Tian X, Liu K, Zhu Z
Scientific reports 2025 Apr 21;15(1):13719
Scientific reports 2025 Apr 21;15(1):13719
Decreased PDLIM1 expression in endothelial cells contributes to the development of intracranial aneurysm.
Yan Y, Qin X, Zheng Y, Jin T, Hu Y, An Q, Leng B
Vascular medicine (London, England) 2024 Feb;29(1):5-16
Vascular medicine (London, England) 2024 Feb;29(1):5-16
Identification and validation of differentially expressed disulfidptosis-related genes in hypertrophic cardiomyopathy.
Fan H, Tan X, Xu S, Zeng Y, Zhang H, Shao T, Zhao R, Zhou P, Bo X, Fan J, Fu Y, Ding X, Zhou Y
Molecular medicine (Cambridge, Mass.) 2024 Dec 19;30(1):249
Molecular medicine (Cambridge, Mass.) 2024 Dec 19;30(1):249
Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB.
Wang Y, Huang Y, Liu J, Zhang J, Xu M, You Z, Peng C, Gong Z, Liu W
EMBO reports 2020 Jan 7;21(1):e48335
EMBO reports 2020 Jan 7;21(1):e48335
Autophagy regulates spermatid differentiation via degradation of PDLIM1.
Shang Y, Wang H, Jia P, Zhao H, Liu C, Liu W, Song Z, Xu Z, Yang L, Wang Y, Li W
Autophagy 2016 Sep;12(9):1575-92
Autophagy 2016 Sep;12(9):1575-92
Autophagy is required for ectoplasmic specialization assembly in sertoli cells.
Liu C, Wang H, Shang Y, Liu W, Song Z, Zhao H, Wang L, Jia P, Gao F, Xu Z, Yang L, Gao F, Li W
Autophagy 2016 May 3;12(5):814-32
Autophagy 2016 May 3;12(5):814-32
Autophagy protects cardiomyocytes from the myocardial ischaemia-reperfusion injury through the clearance of CLP36.
Li S, Liu C, Gu L, Wang L, Shang Y, Liu Q, Wan J, Shi J, Wang F, Xu Z, Ji G, Li W
Open biology 2016 Aug;6(8)
Open biology 2016 Aug;6(8)
CLP36 and RIL recruit α-actinin-1 to stress fibers and differentially regulate stress fiber dynamics in F2408 fibroblasts.
Miyazaki K, Ohno K, Tamura N, Sasaki T, Sato K
Experimental cell research 2012 Aug 15;318(14):1716-25
Experimental cell research 2012 Aug 15;318(14):1716-25
CLP36 interacts with palladin in dorsal root ganglion neurons.
Hasegawa T, Ohno K, Funahashi S, Miyazaki K, Nagano A, Sato K
Neuroscience letters 2010 May 31;476(2):53-7
Neuroscience letters 2010 May 31;476(2):53-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 11674-1-AP( PDLIM1,CLP36 Antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using PDLIM1 antibody 11674-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line