BS8355

antibody from Bioworld Technology, Inc
Targeting: PDLIM1 CLIM1, CLP-36, CLP36, hCLIM1
Provider product page for BS8355
Western blot
Immunohistochemistry

Antibody data

Product number
BS8355 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PDLIM1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PDLIM1.
Description
CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with Actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (a kinase) and recruits Clik1 to Ï«-actinin-1, thereby facilitating the association of Clik1 with Actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88% sequence similarity with its rat counterpart, suggesting a conserved function between species.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PDLIM1 protein structure - BS8355 shown in red.