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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 11648-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11648-2-AP, RRID:AB_2217787
- Product name
- 14-3-3 Epsilon antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated 14-3-3 Epsilon antibody (Cat. #11648-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A Novel Heptapeptide, GPPGPAG Transfers to the Brain, and Ameliorates Memory Dysfunction and Dendritic Atrophy in Alzheimer's Disease Model Mice.
Role of the Chaperone Protein 14-3-3ε in the Regulation of Influenza A Virus-Activated Beta Interferon.
Akt kinase LANCL2 functions as a key driver in EGFR-mutant lung adenocarcinoma tumorigenesis.
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Interactome of the Autoimmune Risk Protein ANKRD55.
Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity.
14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer.
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Specific Alterations in Astrocyte Properties via the GluA2-GAPDH Complex Associated with Multiple Sclerosis.
A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity.
Tohda C, Kogure C, Nomoto K, de Toledo A, Yang X, Hirano E
Frontiers in pharmacology 2021;12:680652
Frontiers in pharmacology 2021;12:680652
Role of the Chaperone Protein 14-3-3ε in the Regulation of Influenza A Virus-Activated Beta Interferon.
Tam EH, Liu YC, Woung CH, Liu HM, Wu GH, Wu CC, Kuo RL
Journal of virology 2021 Sep 27;95(20):e0023121
Journal of virology 2021 Sep 27;95(20):e0023121
Akt kinase LANCL2 functions as a key driver in EGFR-mutant lung adenocarcinoma tumorigenesis.
Lou Y, Xu J, Zhang Y, Zhang W, Zhang X, Gu P, Zhong H, Wang H, Lu J, Han B
Cell death & disease 2021 Feb 10;12(2):170
Cell death & disease 2021 Feb 10;12(2):170
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B
Biochemical pharmacology 2020 Feb;172:113752
Biochemical pharmacology 2020 Feb;172:113752
Interactome of the Autoimmune Risk Protein ANKRD55.
Ugidos N, Mena J, Baquero S, Alloza I, Azkargorta M, Elortza F, Vandenbroeck K
Frontiers in immunology 2019;10:2067
Frontiers in immunology 2019;10:2067
Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity.
Riedl W, Acharya D, Lee JH, Liu G, Serman T, Chiang C, Chan YK, Diamond MS, Gack MU
Cell host & microbe 2019 Oct 9;26(4):493-503.e6
Cell host & microbe 2019 Oct 9;26(4):493-503.e6
14-3-3ζ inhibits heme oxygenase-1 (HO-1) degradation and promotes hepatocellular carcinoma proliferation: involvement of STAT3 signaling.
Song J, Zhang X, Liao Z, Liang H, Chu L, Dong W, Zhang X, Ge Q, Liu Q, Fan P, Zhang Z, Zhang B
Journal of experimental & clinical cancer research : CR 2019 Jan 3;38(1):3
Journal of experimental & clinical cancer research : CR 2019 Jan 3;38(1):3
CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer.
Li H, Jin X, Liu B, Zhang P, Chen W, Li Q
BMC cancer 2019 Aug 22;19(1):826
BMC cancer 2019 Aug 22;19(1):826
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Lu K, Rui G, Liu F, Yang L, Deng X, Shi S, Li Q
Oncology letters 2018 Jan;15(1):338-346
Oncology letters 2018 Jan;15(1):338-346
Specific Alterations in Astrocyte Properties via the GluA2-GAPDH Complex Associated with Multiple Sclerosis.
Lee FHF, Zhang H, Jiang A, Zai CC, Liu F
Scientific reports 2018 Aug 27;8(1):12856
Scientific reports 2018 Aug 27;8(1):12856
A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity.
Chan YK, Gack MU
Nature immunology 2016 May;17(5):523-30
Nature immunology 2016 May;17(5):523-30
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 11648-2-AP(14-3-3E antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using YWHAE antibody 11648-2-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-14-3-3E (IP:11648-2-AP, 3ug; Detection:11648-2-AP 1:1000) with A375 cells lysate 6000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 11648-2-AP(14-3-3E antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
