Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
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- Product number
- 168 - Provider product page
- Provider
- YO Proteins AB
- Proper citation
- YO Proteins Cat#168, RRID:AB_2165333
- Product name
- Rabbit anti-human urokinase polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal rabbit antibody anti-human urokinase (abbokinase, urokinase-type Plasminogen Activator, uPA). The antibody binds to human HMW-scuPA (54 kDa), HMW-tsuPA (52 kDa) and LMW-scuPA (33 kDa) with high apparent affinity (Kd= 0.1 nM) completely inhibiting the ability of urokinase to activate plasminogen. Urokinase reaction with synthetic substrate S2444 is also inhibited. The antibody is highly specific for urokinase, no crossreactions were found with other serine proteases (tissue plasminogen activator, plasmin, trypsin, chymotrypsin, elastase, thrombin). Human whole plasma or plasma proteins do not interfere with its binding to urokinase
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 1 ml
Submitted references Plasmin in nephrotic urine activates the epithelial sodium channel.
FAP-alpha and uPA show different expression patterns in premalignant and malignant esophageal lesions.
Svenningsen P, Bistrup C, Friis UG, Bertog M, Haerteis S, Krueger B, Stubbe J, Jensen ON, Thiesson HC, Uhrenholt TR, Jespersen B, Jensen BL, Korbmacher C, Skøtt O
Journal of the American Society of Nephrology : JASN 2009 Feb;20(2):299-310
Journal of the American Society of Nephrology : JASN 2009 Feb;20(2):299-310
FAP-alpha and uPA show different expression patterns in premalignant and malignant esophageal lesions.
Goscinski MA, Suo Z, Flørenes VA, Vlatkovic L, Nesland JM, Giercksky KE
Ultrastructural pathology 2008 May-Jun;32(3):89-96
Ultrastructural pathology 2008 May-Jun;32(3):89-96
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