335

antibody from YO Proteins AB

Targeting: PLAU UPA, URK

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

335

Provider

YO Proteins AB

Proper citation

YO Proteins Cat#335, RRID:AB_1582714

Product name

Mouse anti-human urokinase monoclonal antibody, clone PGM2005

Antibody type

Monoclonal

Description

Monoclonal antibody (clone PGM2005, IgG1 fraction) anti-human urokinase (abbokinase, urokinase-type Plasminogen Activator, uPA). Binds to human high molecular weight single-chain urokinase type plasminogen activator (HMW-scuPA, 54 kDa), to high molecular weight two-chain urokinase type plasminogen activator (HMW-tcuPA, 52 kDa) and to low molecular weight single-chain urokinase type plasminogen activator (LMW-scuPA, 33kDa) with high affinity (Kd = 0.1 nM) and does inhibit the ability of urokinase to activate plasminogen. Urokinase reaction with synthetic substrate S2444 is not inhibited. Highly specific for urokinase, no cross-reactions were found with other serine proteases (tissue plasminogen activator, plasmin, trypsin, chymotrypsin, elastase, and thrombin). Human plasma or plasma proteins do not interfere with its binding to urokinase

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

1 ml