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Learn339206
antibody from BioLegend
Targeting: SIGLEC7
CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- 339206 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#339206, RRID:AB_2565239
- Product name
- APC anti-human CD328 (Siglec-7)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Siglec-7, also known as p75/AIRM1, is a 75 kD type I transmembrane protein and a member of the family of sialic acid-binding immunoglobulin-like lectins (Siglecs). It is primarily found on NK cells and monocytes. The cytoplasmic domain of Siglec-7 contains immunoreceptor tyrosine-based inhibitory motif (ITIM). CD328 mediates sialic acid-dependent cell-cell binding and functions as an inhibitory receptor of NK cells. CD328 preferentially binds to sialylated glycans with α2,8 disialyl and α2,6 sialyl residues.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antibody clone number
- 6-434
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were stained with CD56 PE and CD328 (clone 6-434) APC (top) or mouse IgG1, κ APC isotype control (bottom).
- Conjugate
- Red dye
