14-5759-37

antibody from Invitrogen Antibodies
Targeting: SIGLEC7 CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2
Provider product page for 14-5759-37
Immunoprecipitation
Flow cytometry
Other assay

Antibody data

Product number
14-5759-37 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD328 (Siglec7) Monoclonal Antibody (eBioQA79 (QA79)), eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The eBioQA79 monoclonal antibody reacts with adhesion inhibitory receptor molecule 1 (AIRM1), also known as sialic acid binding immunoglobulin-like lectin 7 (Siglec-7), p75 and CDw328. AIRM1 is a cell surface receptor that belongs to the sialoadhesin family and displays homology with the myeloid cell antigen CD33. p75/AIRM1 expression is confined to NK cells in lymphoid cells. eBioQA79 crosslinking inhibits NK function. p75/AIRM1 is expressed at various stages of myeloid differentiation. Presence of this protein is a useful way to monitor cellular proliferation and determine proliferative states of cells, especially in diseases such as chronic myeloid leukemia. Applications Reported: This eBioQA79 (QA79) antibody has been reported for use in flow cytometric analysis, and immunoprecipitation. Applications Tested: This eBioQA79 (QA79) antibody has been tested by flow cytometric analysis. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
eBioQA79 (QA79)
Vial size
2 mg
Concentration
0.5 mg/mL
Storage
4° C
SIGLEC7 protein structure - 14-5759-37 shown in red.