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antibody from antibodies-online
Targeting: DICER1
Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Western blot [1]
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- Product number
- ABIN268305 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Dicer 1, Ribonuclease Type III (DICER1) antibody
- Antibody type
- Polyclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 0.1 mg
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma.
A Regulatory miRNA-mRNA Network Is Associated with Tissue Repair Induced by Mesenchymal Stromal Cells in Acute Kidney Injury.
Loss of Dicer1 impairs hepatocyte survival and leads to chronic inflammation and progenitor cell activation.
Reduced DICER1 elicits an interferon response in endometrial cancer cells.
Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype.
Identification of cellular proteins that maintain retroviral epigenetic silencing: evidence for an antiviral response.
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure.
Dicer expression and localization in post-mitotic neurons.
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis.
Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner.
Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP.
Dicer is required for chromosome segregation and gene silencing in fission yeast cells.
Simeoli R, Montague K, Jones HR, Castaldi L, Chambers D, Kelleher JH, Vacca V, Pitcher T, Grist J, Al-Ahdal H, Wong LF, Perretti M, Lai J, Mouritzen P, Heppenstall P, Malcangio M
Nature communications 2017 Nov 24;8(1):1778
Nature communications 2017 Nov 24;8(1):1778
A Regulatory miRNA-mRNA Network Is Associated with Tissue Repair Induced by Mesenchymal Stromal Cells in Acute Kidney Injury.
de Almeida DC, Bassi ÊJ, Azevedo H, Anderson L, Origassa CS, Cenedeze MA, de Andrade-Oliveira V, Felizardo RJ, da Silva RC, Hiyane MI, Semedo P, Dos Reis MA, Moreira-Filho CA, Verjovski-Almeida S, Pacheco-Silva Á, Câmara NO
Frontiers in immunology 2016;7:645
Frontiers in immunology 2016;7:645
Loss of Dicer1 impairs hepatocyte survival and leads to chronic inflammation and progenitor cell activation.
Lu XF, Zhou YJ, Zhang L, Ji HJ, Li L, Shi YJ, Bu H
World journal of gastroenterology 2015 Jun 7;21(21):6591-603
World journal of gastroenterology 2015 Jun 7;21(21):6591-603
Reduced DICER1 elicits an interferon response in endometrial cancer cells.
Chiappinelli KB, Haynes BC, Brent MR, Goodfellow PJ
Molecular cancer research : MCR 2012 Mar;10(3):316-25
Molecular cancer research : MCR 2012 Mar;10(3):316-25
Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype.
Grelier G, Voirin N, Ay AS, Cox DG, Chabaud S, Treilleux I, Léon-Goddard S, Rimokh R, Mikaelian I, Venoux C, Puisieux A, Lasset C, Moyret-Lalle C
British journal of cancer 2009 Aug 18;101(4):673-83
British journal of cancer 2009 Aug 18;101(4):673-83
Identification of cellular proteins that maintain retroviral epigenetic silencing: evidence for an antiviral response.
Poleshko A, Palagin I, Zhang R, Boimel P, Castagna C, Adams PD, Skalka AM, Katz RA
Journal of virology 2008 Mar;82(5):2313-23
Journal of virology 2008 Mar;82(5):2313-23
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure.
Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ
Proceedings of the National Academy of Sciences of the United States of America 2008 Feb 12;105(6):2111-6
Proceedings of the National Academy of Sciences of the United States of America 2008 Feb 12;105(6):2111-6
Dicer expression and localization in post-mitotic neurons.
Barbato C, Ciotti MT, Serafino A, Calissano P, Cogoni C
Brain research 2007 Oct 17;1175:17-27
Brain research 2007 Oct 17;1175:17-27
MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis.
Grivna ST, Pyhtila B, Lin H
Proceedings of the National Academy of Sciences of the United States of America 2006 Sep 5;103(36):13415-20
Proceedings of the National Academy of Sciences of the United States of America 2006 Sep 5;103(36):13415-20
Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner.
Lugli G, Larson J, Martone ME, Jones Y, Smalheiser NR
Journal of neurochemistry 2005 Aug;94(4):896-905
Journal of neurochemistry 2005 Aug;94(4):896-905
Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K
Current biology : CB 2003 Jan 8;13(1):41-6
Current biology : CB 2003 Jan 8;13(1):41-6
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP.
Zhang H, Kolb FA, Brondani V, Billy E, Filipowicz W
The EMBO journal 2002 Nov 1;21(21):5875-85
The EMBO journal 2002 Nov 1;21(21):5875-85
Dicer is required for chromosome segregation and gene silencing in fission yeast cells.
Provost P, Silverstein RA, Dishart D, Walfridsson J, Djupedal I, Kniola B, Wright A, Samuelsson B, Radmark O, Ekwall K
Proceedings of the National Academy of Sciences of the United States of America 2002 Dec 24;99(26):16648-53
Proceedings of the National Academy of Sciences of the United States of America 2002 Dec 24;99(26):16648-53
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