Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15058-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15058-1-AP, RRID:AB_2059787
- Product name
- ARPC2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ARPC2 antibody (Cat. #15058-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Aberrant cortex contractions impact mammalian oocyte quality.
Localization of Kif1c mRNA to cell protrusions dictates binding partner specificity of the encoded protein.
Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction.
Feedback-Driven Mechanisms Between Phosphorylated Caveolin-1 and Contractile Actin Assemblies Instruct Persistent Cell Migration.
WDR63 inhibits Arp2/3-dependent actin polymerization and mediates the function of p53 in suppressing metastasis.
RBM3 upregulates ARPC2 by binding the 3'UTR and contributes to breast cancer progression.
The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse.
α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.
Nikalayevich E, Letort G, de Labbey G, Todisco E, Shihabi A, Turlier H, Voituriez R, Yahiatene M, Pollet-Villard X, Innocenti M, Schuh M, Terret ME, Verlhac MH
Developmental cell 2024 Apr 8;59(7):841-852.e7
Developmental cell 2024 Apr 8;59(7):841-852.e7
Localization of Kif1c mRNA to cell protrusions dictates binding partner specificity of the encoded protein.
Norris ML, Mendell JT
Genes & development 2023 Mar 1;37(5-6):191-203
Genes & development 2023 Mar 1;37(5-6):191-203
Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction.
Chang Y, Zhang J, Huo X, Qu X, Xia C, Huang K, Xie F, Wang N, Wei X, Jia Q
Cell reports 2022 Feb 15;38(7):110390
Cell reports 2022 Feb 15;38(7):110390
Feedback-Driven Mechanisms Between Phosphorylated Caveolin-1 and Contractile Actin Assemblies Instruct Persistent Cell Migration.
Shi X, Wen Z, Wang Y, Liu YJ, Shi K, Jiu Y
Frontiers in cell and developmental biology 2021;9:665919
Frontiers in cell and developmental biology 2021;9:665919
WDR63 inhibits Arp2/3-dependent actin polymerization and mediates the function of p53 in suppressing metastasis.
Zhao K, Wang D, Zhao X, Wang C, Gao Y, Liu K, Wang F, Wu X, Wang X, Sun L, Zang J, Mei Y
EMBO reports 2020 Apr 3;21(4):e49269
EMBO reports 2020 Apr 3;21(4):e49269
RBM3 upregulates ARPC2 by binding the 3'UTR and contributes to breast cancer progression.
Chen P, Yue X, Xiong H, Lu X, Ji Z
International journal of oncology 2019 Apr;54(4):1387-1397
International journal of oncology 2019 Apr;54(4):1387-1397
The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse.
Gokhale A, Hartwig C, Freeman AH, Das R, Zlatic SA, Vistein R, Burch A, Carrot G, Lewis AF, Nelms S, Dickman DK, Puthenveedu MA, Cox DN, Faundez V
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Dec 7;36(49):12393-12411
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Dec 7;36(49):12393-12411
α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.
Paul NR, Allen JL, Chapman A, Morlan-Mairal M, Zindy E, Jacquemet G, Fernandez del Ama L, Ferizovic N, Green DM, Howe JD, Ehler E, Hurlstone A, Caswell PT
The Journal of cell biology 2015 Sep 14;210(6):1013-31
The Journal of cell biology 2015 Sep 14;210(6):1013-31
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 15058-1-AP(ARPC2 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using ARPC2 antibody 15058-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 15058-1-AP(ARPC2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 15058-1-AP(ARPC2 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue