648202

antibody from BioLegend
Targeting: PRDM1 BLIMP1, PRDI-BF1
Provider product page for 648202
Western blot
ELISA
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
648202 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#648202, RRID:AB_2300132
Product name
Purified anti-Blimp-1
Antibody type
Monoclonal
Antigen
Recombinant GST-blimp-1 protein
Description
Blimp-1 is a 98 Kd protein containing five Kuppel-type zinc finger domains that confer sequence specific DNA binding.  It has been postulated to be a master regulator of terminal B cell differentiation. In the BCL-1 lymphoma model of differentiation from mature B cells to plasma cells, ectopic expression of Blimp-1 is sufficient to cause terminal differentiation manifested by loss of surface immunoglobulin, IgM secretion, expression of syndecan-1 and cessation of cell division. Recently, it is reported that Blimp-1 is also involved in T cell differentiation and T cell homeostasis and suppression of IL-2 production.
Reactivity
Human, Mouse
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4 °C.
PRDM1 protein structure - 648202 shown in red.