AMM02344G

antibody from Leading Biology

Targeting: RET CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM02344G

Provider

Leading Biology

Product name

RET Antibody (Ascites)

Antibody type

Monoclonal

Description

This gene, a member of the cadherin superfamily, encodesone of the receptor tyrosine kinases, which are cell-surfacemolecules that transduce signals for cell growth anddifferentiation. This gene plays a crucial role in neural crestdevelopment, and it can undergo oncogenic activation in vivo and invitro by cytogenetic rearrangement. Mutations in this gene areassociated with the disorders multiple endocrine neoplasia, typeIIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease,and medullary thyroid carcinoma. Two transcript variants encodingdifferent isoforms have been found for this gene. Additionaltranscript variants have been described but their biologicalvalidity has not been confirmed.

Reactivity

Human

Host

Mouse

Isotype

IgM

Antibody clone number

188CT11.2.3

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.