ABIN350705

antibody from antibodies-online

Targeting: P2RX7 MGC20089, P2X7

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN350705

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN350705, RRID:AB_10782696

Product name

anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 40-105) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide from aa region 40-105 of mouse P2X7 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in human and shares 95% identity with rat's.

Description

Whole serum

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 40-105

Vial size

100 μL

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Handling

Avoid freeze and thaw cycles.

References

Submitted references

A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor.

Gu BJ, Zhang W, Worthington RA, Sluyter R, Dao-Ung P, Petrou S, Barden JA, Wiley JS
The Journal of biological chemistry 2001 Apr 6;276(14):11135-42

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Cloning and functional characterisation of the mouse P2X7 receptor.

Chessell IP, Simon J, Hibell AD, Michel AD, Barnard EA, Humphrey PP
FEBS letters 1998 Nov 13;439(1-2):26-30

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The permeabilizing ATP receptor, P2X7. Cloning and expression of a human cDNA.

Rassendren F, Buell GN, Virginio C, Collo G, North RA, Surprenant A
The Journal of biological chemistry 1997 Feb 28;272(9):5482-6