Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB16250 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB16250, RRID:AB_10696397
- Product name
- P2RX7 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Goat polyclonal antibody raised against synthetic peptide of P2RX7.
- Antigen sequence
YETNKVTRIQSMNY-C
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Activated microglia in ischemic stroke penumbra upregulate MCP-1 and CCR2 expression in response to lysophosphatidylcholine derived from adjacent neurons and astrocytes.
The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner.
Inose Y, Kato Y, Kitagawa K, Uchiyama S, Shibata N
Neuropathology : official journal of the Japanese Society of Neuropathology 2015 Jun;35(3):209-23
Neuropathology : official journal of the Japanese Society of Neuropathology 2015 Jun;35(3):209-23
The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner.
Tomasinsig L, Pizzirani C, Skerlavaj B, Pellegatti P, Gulinelli S, Tossi A, Di Virgilio F, Zanetti M
The Journal of biological chemistry 2008 Nov 7;283(45):30471-81
The Journal of biological chemistry 2008 Nov 7;283(45):30471-81
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- P2RX7 polyclonal antibody (Cat # PAB16250) staining (0.3 ug/mL) of human brain (frontal cortex) lysate (35 ug protein in RIPA buffer) with (Lane 2) and without (Lane 1) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- P2RX7 polyclonal antibody (Cat # PAB16250) (3.8 ug/mL) staining of paraffin embedded human brain cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)