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- Antibody Data
- Antigen structure
- References [16]
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- Product number
- 28207-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- P2RX7 antibody
- Antibody type
- Polyclonal
- Description
- P2RX7 antibody (Cat. #28207-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The microRNA-211-5p/P2RX7/ERK/GPX4 axis regulates epilepsy-associated neuronal ferroptosis and oxidative stress.
Baicalin inhibits monosodium urate crystal-induced pyroptosis in renal tubular epithelial cell line through Panx-1/P2X7 pathways: Molecular docking, molecular dynamics, and in vitro experiments.
P2X(7)R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes.
Asiaticoside hampers epithelial-mesenchymal transition by promoting PPARG expression and suppressing P2RX7-mediated TGF-β/Smad signaling in triple-negative breast cancer.
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Aluminum induces neuroinflammation via P2X7 receptor activating NLRP3 inflammasome pathway.
Blocking P2RX7 Attenuates Ferroptosis in Endothelium and Reduces HG-induced Hemorrhagic Transformation After MCAO by Inhibiting ERK1/2 and P53 Signaling Pathways.
Co-exposure to cadmium and microplastics promotes liver fibrosis through the hemichannels -ATP-P2X7 pathway.
Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH.
Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndrome.
Microglial NLRP3 inflammasome activation mediates diabetes-induced depression-like behavior via triggering neuroinflammation.
Progesterone Reduces ATP-Induced Pyroptosis of SH-SY5Y Cells.
Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.
Apelin-13/APJ induces cardiomyocyte hypertrophy by activating the Pannexin-1/P2X7 axis and FAM134B-dependent reticulophagy.
A438079 affects colorectal cancer cell proliferation, migration, apoptosis, and pyroptosis by inhibiting the P2X7 receptor.
The role of P2X7 receptor in prognosis and metastasis of colorectal cancer.
Li X, Quan P, Si Y, Liu F, Fan Y, Ding F, Sun L, Liu H, Huang S, Sun L, Yang F, Yao L
Journal of neuroinflammation 2024 Jan 8;21(1):13
Journal of neuroinflammation 2024 Jan 8;21(1):13
Baicalin inhibits monosodium urate crystal-induced pyroptosis in renal tubular epithelial cell line through Panx-1/P2X7 pathways: Molecular docking, molecular dynamics, and in vitro experiments.
Fu W, Liu Z, Wang Y, Li X, Yu X, Li Y, Yu Z, Qiu Y, Mei Z, Xu L
Chemical biology & drug design 2024 Apr;103(4):e14522
Chemical biology & drug design 2024 Apr;103(4):e14522
P2X(7)R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes.
Beltran-Lobo P, Hughes MM, Troakes C, Croft CL, Rupawala H, Jutzi D, Ruepp MD, Jimenez-Sanchez M, Perkinton MS, Kassiou M, Golde TE, Hanger DP, Verkhratsky A, Perez-Nievas BG, Noble W
Brain, behavior, and immunity 2023 Nov;114:414-429
Brain, behavior, and immunity 2023 Nov;114:414-429
Asiaticoside hampers epithelial-mesenchymal transition by promoting PPARG expression and suppressing P2RX7-mediated TGF-β/Smad signaling in triple-negative breast cancer.
Huang X, Jia Z, Li X, Hu Z, Yu X, Xia J
Phytotherapy research : PTR 2023 May;37(5):1771-1786
Phytotherapy research : PTR 2023 May;37(5):1771-1786
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Sun W, Wang Q, Zhang R, Zhang N
Food & function 2023 Jul 31;14(15):7247-7269
Food & function 2023 Jul 31;14(15):7247-7269
Aluminum induces neuroinflammation via P2X7 receptor activating NLRP3 inflammasome pathway.
Zhu X, Hao W, Liu Z, Song Y, Hao C, Wu S, Lu X, Yang J, Jin C
Ecotoxicology and environmental safety 2023 Jan 1;249:114373
Ecotoxicology and environmental safety 2023 Jan 1;249:114373
Blocking P2RX7 Attenuates Ferroptosis in Endothelium and Reduces HG-induced Hemorrhagic Transformation After MCAO by Inhibiting ERK1/2 and P53 Signaling Pathways.
Liu C, Tian Q, Wang J, He P, Han S, Guo Y, Yang C, Wang G, Wei H, Li M
Molecular neurobiology 2023 Feb;60(2):460-479
Molecular neurobiology 2023 Feb;60(2):460-479
Co-exposure to cadmium and microplastics promotes liver fibrosis through the hemichannels -ATP-P2X7 pathway.
Sun J, Qu H, Ali W, Chen Y, Wang T, Ma Y, Yuan Y, Gu J, Bian J, Liu Z, Zou H
Chemosphere 2023 Dec;344:140372
Chemosphere 2023 Dec;344:140372
Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH.
Liu Y, Yao C, Sheng B, Zhi S, Chen X, Ding P, Zhang J, Tao Z, Li W, Zhuang Z, Mao J, Peng Z, Yan H, Jin W
Translational stroke research 2023 Dec 26;
Translational stroke research 2023 Dec 26;
Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndrome.
Shen C, Jiang Y, Lin J, He Y, Liu Y, Fang D
Journal of bioenergetics and biomembranes 2023 Aug;55(4):313-322
Journal of bioenergetics and biomembranes 2023 Aug;55(4):313-322
Microglial NLRP3 inflammasome activation mediates diabetes-induced depression-like behavior via triggering neuroinflammation.
Su WJ, Li JM, Zhang T, Cao ZY, Hu T, Zhong SY, Xu ZY, Gong H, Jiang CL
Progress in neuro-psychopharmacology & biological psychiatry 2023 Aug 30;126:110796
Progress in neuro-psychopharmacology & biological psychiatry 2023 Aug 30;126:110796
Progesterone Reduces ATP-Induced Pyroptosis of SH-SY5Y Cells.
Cui C, Wang X, Zhang S, Wu H, Li M, Dong L, Yan C, Li D
BioMed research international 2022;2022:4827444
BioMed research international 2022;2022:4827444
Salidroside Ameliorates Depression by Suppressing NLRP3-Mediated Pyroptosis via P2X7/NF-κB/NLRP3 Signaling Pathway.
Chai Y, Cai Y, Fu Y, Wang Y, Zhang Y, Zhang X, Zhu L, Miao M, Yan T
Frontiers in pharmacology 2022;13:812362
Frontiers in pharmacology 2022;13:812362
Apelin-13/APJ induces cardiomyocyte hypertrophy by activating the Pannexin-1/P2X7 axis and FAM134B-dependent reticulophagy.
Yang Y, Zhang K, Huang S, Chen W, Mao H, Ouyang X, Chen L, Li L
Journal of cellular physiology 2022 Apr;237(4):2230-2248
Journal of cellular physiology 2022 Apr;237(4):2230-2248
A438079 affects colorectal cancer cell proliferation, migration, apoptosis, and pyroptosis by inhibiting the P2X7 receptor.
Zhang Y, Li F, Wang L, Lou Y
Biochemical and biophysical research communications 2021 Jun 18;558:147-153
Biochemical and biophysical research communications 2021 Jun 18;558:147-153
The role of P2X7 receptor in prognosis and metastasis of colorectal cancer.
Zhang Y, Ding J, Wang L
Advances in medical sciences 2019 Sep;64(2):388-394
Advances in medical sciences 2019 Sep;64(2):388-394
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