Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB100-2567 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-2567, RRID:AB_10000563
- Product name
- Rabbit Polyclonal CDT1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 ul
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation.
A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication.
MCM proteins are negative regulators of hypoxia-inducible factor 1.
The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing.
Histamine suppresses fibulin-5 and insulin-like growth factor-II receptor expression in melanoma.
Singh RK, Lamplugh ZL, Lang F, Yuan Y, Lieberman P, You J, Robertson ES
PLoS pathogens 2019 Sep;15(9):e1008025
PLoS pathogens 2019 Sep;15(9):e1008025
A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication.
Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL
Science signaling 2013 Feb 12;6(262):ra10
Science signaling 2013 Feb 12;6(262):ra10
MCM proteins are negative regulators of hypoxia-inducible factor 1.
Hubbi ME, Luo W, Baek JH, Semenza GL
Molecular cell 2011 Jun 10;42(5):700-12
Molecular cell 2011 Jun 10;42(5):700-12
The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing.
Kim Y, Starostina NG, Kipreos ET
Genes & development 2008 Sep 15;22(18):2507-19
Genes & development 2008 Sep 15;22(18):2507-19
Histamine suppresses fibulin-5 and insulin-like growth factor-II receptor expression in melanoma.
Pos Z, Wiener Z, Pocza P, Racz M, Toth S, Darvas Z, Molnar V, Hegyesi H, Falus A
Cancer research 2008 Mar 15;68(6):1997-2005
Cancer research 2008 Mar 15;68(6):1997-2005
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CDT1 Antibody [NB100-2567] - Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Affinity purified rabbit anti- CDT1 antibody (NB100-2567) used for WB at 1 ug/mL (A and B) and used for IP at 3 ug/mg lysate (B).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CDT1 Antibody [NB100-2567] - Human B cells. KSHV infection protects CDT1 from hypoxia mediated degradation. Mock or KSHV infected cells were grown under normoxic or hypoxic condition followed by measuring CDT1 levels. Western blot image submitted by a verified customer review.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CDT1 Antibody [NB100-2567] - Human islet cell carcinoma. Antibody used at a dilution of 1:1000 (1ug/mL).