HPA017389

antibody from Atlas Antibodies

Targeting: CAMKK2 CAMKK, CAMKKB, KIAA0787, MGC15254

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA017389

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA017389, RRID:AB_1845956

Product name

Anti-CAMKK2

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human CAMKK2, Gene description: calcium/calmodulin-dependent protein kinase kinase 2, beta, Alternative Gene Names: CAMKK, CAMKKB, KIAA0787, MGC15254, Validated applications: WB, IHC, ICC, Uniprot ID: Q96RR4, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.4 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Targeting CaMKK2 Inhibits Actin Cytoskeletal Assembly to Suppress Cancer Metastasis.

Mukherjee D, Previs RA, Haines C, Al Abo M, Juras PK, Strickland KC, Chakraborty B, Artham S, Whitaker RS, Hebert K, Fontenot J, Patierno SR, Freedman JA, Lau FH, Burow ME, Chang CY, McDonnell DP
Cancer research 2023 Sep 1;83(17):2889-2907

---

Computational analysis of cortical neuronal excitotoxicity in a large animal model of neonatal brain injury

Kratimenos P, Vij A, Vidva R, Koutroulis I, Delivoria-Papadopoulos M, Gallo V, Sathyanesan A
Journal of Neurodevelopmental Disorders 2022;14(1)

---

The effects of UCP2 on autophagy through the AMPK signaling pathway in septic cardiomyopathy and the underlying mechanism

Mao J, Su L, Li D, Zhang H, Wang X, Liu D
Annals of Translational Medicine 2021;9(3):259-259

---

IQGAP1 binds AMPK and is required for maximum AMPK activation

Hedman A, Li Z, Gorisse L, Parvathaneni S, Morgan C, Sacks D
Journal of Biological Chemistry 2021;296

---

CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation.

Stewart LM, Gerner L, Rettel M, Stein F, Burrows JF, Mills IG, Evergren E
Cell death & disease 2021 Nov 1;12(11):1040

---

CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer

Racioppi L, Nelson E, Huang W, Mukherjee D, Lawrence S, Lento W, Masci A, Jiao Y, Park S, York B, Liu Y, Baek A, Drewry D, Zuercher W, Bertani F, Businaro L, Geradts J, Hall A, Means A, Chao N, Chang C, McDonnell D
Nature Communications 2019;10(1)

---

Loss of Ca2+/Calmodulin Dependent Protein Kinase Kinase 2 Leads to Aberrant Transferrin Phosphorylation and Trafficking: A Potential Biomarker for Alzheimer's Disease

Sabbir M
Frontiers in Molecular Biosciences 2018;5

---

Functional Proteomics and Deep Network Interrogation Reveal a Complex Mechanism of Action of Midostaurin in Lung Cancer Cells

Ctortecka C, Palve V, Kuenzi B, Fang B, Sumi N, Izumi V, Novakova S, Kinose F, Remsing Rix L, Haura E, Koomen J, Rix U
Molecular & Cellular Proteomics 2018;17(12):2434-2447

---

c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks

Barfeld S, Urbanucci A, Itkonen H, Fazli L, Hicks J, Thiede B, Rennie P, Yegnasubramanian S, DeMarzo A, Mills I
EBioMedicine 2017;18

---

Polypharmacology-based ceritinib repurposing using integrated functional proteomics

Kuenzi B, Remsing Rix L, Stewart P, Fang B, Kinose F, Bryant A, Boyle T, Koomen J, Haura E, Rix U
Nature Chemical Biology 2017;13(12):1222-1231

---

Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma

Subbannayya Y, Syed N, Barbhuiya M, Raja R, Marimuthu A, Sahasrabuddhe N, Pinto S, Manda S, Renuse S, Manju H, Zameer M, Sharma J, Brait M, Srikumar K, Roa J, Vijaya Kumar M, Kumar K, Prasad T, Ramaswamy G, Kumar R, Pandey A, Gowda H, Chatterjee A
Cancer Biology & Therapy 2015;16(2):336-345

---

Role of Ca2+/Calmodulin-Dependent Protein Kinase Kinase in Adrenal Aldosterone Production

Rainey W, Nishimoto K, Chen A, Nanba K
Endocrinology 2015;156(5):1750-1756

---

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.

Massie CE, Lynch A, Ramos-Montoya A, Boren J, Stark R, Fazli L, Warren A, Scott H, Madhu B, Sharma N, Bon H, Zecchini V, Smith DM, Denicola GM, Mathews N, Osborne M, Hadfield J, Macarthur S, Adryan B, Lyons SK, Brindle KM, Griffiths J, Gleave ME, Rennie PS, Neal DE, Mills IG
The EMBO journal 2011 May 20;30(13):2719-33