Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN2842226 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, beta Polypeptide (YWHAB) (AA 217-246), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 217-246, C-Term
- Antibody clone number
- RB4064
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references 14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity.
Immunoexpression of 14-3-3 proteins in glial cytoplasmic inclusions of multiple system atrophy.
14-3-3beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin.
The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3.
14-3-3 binding to the IGF-1 receptor is mediated by serine autophosphorylation.
Cavet ME, Lehoux S, Berk BC
The Journal of biological chemistry 2003 May 16;278(20):18376-83
The Journal of biological chemistry 2003 May 16;278(20):18376-83
Immunoexpression of 14-3-3 proteins in glial cytoplasmic inclusions of multiple system atrophy.
Komori T, Ishizawa K, Arai N, Hirose T, Mizutani T, Oda M
Acta neuropathologica 2003 Jul;106(1):66-70
Acta neuropathologica 2003 Jul;106(1):66-70
14-3-3beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin.
Shumway SD, Li Y, Xiong Y
The Journal of biological chemistry 2003 Jan 24;278(4):2089-92
The Journal of biological chemistry 2003 Jan 24;278(4):2089-92
The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3.
Li Y, Inoki K, Vacratsis P, Guan KL
The Journal of biological chemistry 2003 Apr 18;278(16):13663-71
The Journal of biological chemistry 2003 Apr 18;278(16):13663-71
14-3-3 binding to the IGF-1 receptor is mediated by serine autophosphorylation.
Parvaresch S, Yesilkaya T, Baer K, Al-Hasani H, Klein HW
FEBS letters 2002 Dec 18;532(3):357-62
FEBS letters 2002 Dec 18;532(3):357-62
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC