Antibody data

Product number
Ab086611 - Provider product page
Provider
Aladdin Scientific
Product name
14-3-3 sigma/SFN Antibody
Antibody type
Polyclonal
Description
Rabbit anti Human 14-3-3 sigma/SFN Antibody, Polyclonal, could be used for WB and so on.ApplicationWB: 0.01-2 µg/mLProtein FunctionAdapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.p53-regulated inhibitor of G2/M progression.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
AA 1-248
Vial size
100_l,10_l,1ml,20_l,50_l
Concentration
Lot by Lot
Storage
Store at 4_ short term (1-2 weeks). Store at -20_ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
SFN protein structure - Ab086611 shown in red.