13511-1-AP

antibody from Proteintech Group

Targeting: B2M

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

13511-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#13511-1-AP, RRID:AB_2062735

Product name

Beta-2-Microglobulin antibody

Antibody type

Polyclonal

Description

Beta-2-Microglobulin antibody (Cat. #13511-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

RNF26 regulating tumor immunogenicity of hepatocellular carcinoma by degrading GRP78 and instigating ER stress.

Luo J, Zhuo H, Zheng M, Fang Y, Wang X, Jin Y, Li Y, Du S, Wang J, Xue C, Jiang R, Li G
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101375

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CircRNA GRAMD4 induces NBR1 expression to promote autophagy and immune escape in renal cell carcinoma.

Zhou M, Chen M, Zheng Z, Li Q, Liao L, Wang Y, Xu Y, Shu G, Luo J, Yang T, Zhang J
Autophagy 2025 Nov;21(11):2332-2352

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Radiation regulates the expression of HLA-I in esophageal squamous cell carcinoma through interferon-γ.

Shao S, Pan C, Ni Q, Huang J
Scientific reports 2025 Nov 18;15(1):40577

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Quantitative Proteome Analysis of Plasma Extracellular Vesicles Identifies Three Proteins with Potential Diagnostic Value for Mycobacterium bovis Infection in Cows.

Zhou H, Wu W, Zhang Q, Zhang T, Jiang S, Liu H, Ma Y, Chang L, Xie Y, Zhu J, Zhou D, Zhang Y, Xu P
Journal of proteome research 2025 Jun 6;24(6):2926-2938

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The human testis-specific protein Y-linked (TSPY) is a male-specific cancer-testis antigen capable of eliciting significant immune responses and elimination of positive tumor cells in hepatocellular carcinoma.

Kido T, Lau YC
Cell & bioscience 2025 Jun 25;15(1):88

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A novel mouse model of chronic neuronopathic Gaucher disease exhibits Parkinson's disease-like phenotypes.

Wen S, Li Y, Xiang W, Shen F, Jiang N, Ma D, Zhang J
Neurobiology of disease 2025 Jun 1;209:106899

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Celastrol enhanced CD8+T cell immunity in melanoma by targeting SHP2 and upregulating MHC-I.

Kong Q, Liu S, He S, Luo Z, Lei R, Wang R, Liu X, Wu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156731

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The emerging fungal pathogen Candida auris induces IFNγ to colonize mammalian hair follicles.

Merrill ED, Prudent V, Moghadam P, Rodriguez A, Hurabielle C, Wells EKC, Basso P, Scharschmidt TC, Rosenblum MD, Molofsky AB, Noble SM
bioRxiv : the preprint server for biology 2025 Jan 18;

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Robust single-nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity.

So J, Strobel O, Wann J, Kim K, Paul A, Acri DJ, Dabin LC, Kim J, Peng G, Roh HC
eLife 2025 Jan 13;13

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Maternal Gestational Diabetes Mellitus and High-Fat Diet Influenced Hepatic Polyunsaturated Fatty Acids Profile in the Offspring of C57BL/6J Mice.

Gong J, Xu W, Chen Y, Chen S, Wu Y, Chen Y, Li Y, He Y, Yu H, Xie L
Molecular nutrition & food research 2024 Oct;68(19):e2400386

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Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models.

Oravecz-Wilson K, Lauder E, Taylor A, Maneix L, Van Nostrand JL, Sun Y, Li L, Zhao D, Liu C, Reddy P
The Journal of clinical investigation 2024 Mar 1;134(5)

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Silencing HE4 alleviates the renal fibrosis in lupus nephritis mice by regulating the C3/MMPs/prss axis.

Li Y, Zhong X, Yang F
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4823-4831

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Single-cell transcriptomics reveals ferrimagnetic vortex iron oxide nanoring-mediated mild magnetic hyperthermia exerts antitumor effects by alleviating macrophage suppression in breast cancer.

Xi P, Liu S, Tang J, Wang X, Liu Y, Wang X, Hu S, Wang K, Li W, Cai Z, Shi H, Dai P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:115954

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Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma.

Chen W, Liao Y, Sun P, Tu J, Zou Y, Fang J, Chen Z, Li H, Chen J, Peng Y, Wen L, Xie X
Journal of translational medicine 2024 Jan 16;22(1):66

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IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion.

Herhaus L, Gestal-Mato U, Eapen VV, Mačinković I, Bailey HJ, Prieto-Garcia C, Misra M, Jacomin AC, Ammanath AV, Bagarić I, Michaelis J, Vollrath J, Bhaskara RM, Bündgen G, Covarrubias-Pinto A, Husnjak K, Zöller J, Gikandi A, Ribičić S, Bopp T, van der Heden van Noort GJ, Langer JD, Weigert A, Harper JW, Mancias JD, Dikic I
Cell 2024 Dec 12;187(25):7285-7302.e29

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Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity.

So J, Strobel O, Wann J, Kim K, Paul A, Acri DJ, Dabin LC, Peng G, Kim J, Roh HC
bioRxiv : the preprint server for biology 2024 Aug 12;

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Transcriptome analysis revealed the new mechanism of the intra-myocardial injectable alginate-hydrogel in the treatment of ventricular function degradation.

Wang H, Zhou T, Ma W, Zheng J, Cao Z, He C, Lemos PA, Luo J
Journal of thoracic disease 2024 Apr 30;16(4):2443-2459

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Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.

Peng L, Zhou L, Li H, Zhang X, Li S, Wang K, Yang M, Ma X, Zhang D, Xiang S, Duan Y, Wang T, Sun C, Wang C, Lu D, Qian M, Wang Z
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Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.

Wang Y, He X, Xue M, Sun W, He Q, Jin J
Free radical research 2023 May-Jun;57(6-12):413-429

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B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy.

Zhao Y, Cao Y, Chen Y, Wu L, Hang H, Jiang C, Zhou X
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Single-cell transcriptomics following ischemic injury identifies a role for B2M in cardiac repair.

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Biomaterials science 2021 Aug 21;9(16):5551-5558

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β2-microglobulin as a biomarker of pulmonary fibrosis development in COPD patients.

Wu Z, Yan M, Zhang M, Wu N, Ma G, Wang B, Fan Y, Du X, Ding C, Liu Y
Aging 2020 Dec 21;13(1):1251-1263

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Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.

Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H
Nature communications 2018 Jan 30;9(1):433

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Heritable multiplex genetic engineering in rats using CRISPR/Cas9.

Ma Y, Shen B, Zhang X, Lu Y, Chen W, Ma J, Huang X, Zhang L
PloS one 2014;9(3):e89413

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HeLa cells were subjected to SDS PAGE followed by western blot with 13511-1-AP(B2M antibody) at dilution of 1:1000

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human stomach cancer using 13511-1-AP(B2M antibody) at dilution of 1:100 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The Beta-2-microglobulin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Beta-2-microglobulin. This antibody recognizes human, mouse antigen. The Beta-2-microglobulin antibody has been validated for the following applications: ELISA, WB, IHC analysis.

Appendix

13511-1-AP.pdf

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