Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13511-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13511-1-AP, RRID:AB_2062735
- Product name
- Beta-2-Microglobulin antibody
- Antibody type
- Polyclonal
- Description
- Beta-2-Microglobulin antibody (Cat. #13511-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models.
Silencing HE4 alleviates the renal fibrosis in lupus nephritis mice by regulating the C3/MMPs/prss axis.
Single-cell transcriptomics reveals ferrimagnetic vortex iron oxide nanoring-mediated mild magnetic hyperthermia exerts antitumor effects by alleviating macrophage suppression in breast cancer.
Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma.
Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity.
Transcriptome analysis revealed the new mechanism of the intra-myocardial injectable alginate-hydrogel in the treatment of ventricular function degradation.
Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.
Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.
Nintedanib enhances the efficacy of PD-L1 blockade by upregulating MHC-I and PD-L1 expression in tumor cells.
Cytoglobin inhibits non-thermal plasma-induced apoptosis in melanoma cells through regulation of the NRF2-mediated antioxidant response.
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Cytoglobin Silencing Promotes Melanoma Malignancy but Sensitizes for Ferroptosis and Pyroptosis Therapy Response.
B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy.
Single-cell transcriptomics following ischemic injury identifies a role for B2M in cardiac repair.
Impact of beta-2 microglobulin expression on the survival of glioma patients via modulating the tumor immune microenvironment.
Enhanced β2-microglobulin binding of a "navigator" molecule bearing a single-chain variable fragment antibody for artificial switching of metabolic processing pathways.
β2-microglobulin as a biomarker of pulmonary fibrosis development in COPD patients.
Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.
Heritable multiplex genetic engineering in rats using CRISPR/Cas9.
Oravecz-Wilson K, Lauder E, Taylor A, Maneix L, Van Nostrand JL, Sun Y, Li L, Zhao D, Liu C, Reddy P
The Journal of clinical investigation 2024 Mar 1;134(5)
The Journal of clinical investigation 2024 Mar 1;134(5)
Silencing HE4 alleviates the renal fibrosis in lupus nephritis mice by regulating the C3/MMPs/prss axis.
Li Y, Zhong X, Yang F
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4823-4831
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jul;397(7):4823-4831
Single-cell transcriptomics reveals ferrimagnetic vortex iron oxide nanoring-mediated mild magnetic hyperthermia exerts antitumor effects by alleviating macrophage suppression in breast cancer.
Xi P, Liu S, Tang J, Wang X, Liu Y, Wang X, Hu S, Wang K, Li W, Cai Z, Shi H, Dai P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:115954
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:115954
Construction of an ER stress-related prognostic signature for predicting prognosis and screening the effective anti-tumor drug in osteosarcoma.
Chen W, Liao Y, Sun P, Tu J, Zou Y, Fang J, Chen Z, Li H, Chen J, Peng Y, Wen L, Xie X
Journal of translational medicine 2024 Jan 16;22(1):66
Journal of translational medicine 2024 Jan 16;22(1):66
Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity.
So J, Strobel O, Wann J, Kim K, Paul A, Acri DJ, Dabin LC, Peng G, Kim J, Roh HC
bioRxiv : the preprint server for biology 2024 Aug 12;
bioRxiv : the preprint server for biology 2024 Aug 12;
Transcriptome analysis revealed the new mechanism of the intra-myocardial injectable alginate-hydrogel in the treatment of ventricular function degradation.
Wang H, Zhou T, Ma W, Zheng J, Cao Z, He C, Lemos PA, Luo J
Journal of thoracic disease 2024 Apr 30;16(4):2443-2459
Journal of thoracic disease 2024 Apr 30;16(4):2443-2459
Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.
Peng L, Zhou L, Li H, Zhang X, Li S, Wang K, Yang M, Ma X, Zhang D, Xiang S, Duan Y, Wang T, Sun C, Wang C, Lu D, Qian M, Wang Z
Cell reports 2024 Apr 23;43(4):114003
Cell reports 2024 Apr 23;43(4):114003
Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.
Wang Y, He X, Xue M, Sun W, He Q, Jin J
Free radical research 2023 May-Jun;57(6-12):413-429
Free radical research 2023 May-Jun;57(6-12):413-429
Nintedanib enhances the efficacy of PD-L1 blockade by upregulating MHC-I and PD-L1 expression in tumor cells.
Tu J, Xu H, Ma L, Li C, Qin W, Chen X, Yi M, Sun L, Liu B, Yuan X
Theranostics 2022;12(2):747-766
Theranostics 2022;12(2):747-766
Cytoglobin inhibits non-thermal plasma-induced apoptosis in melanoma cells through regulation of the NRF2-mediated antioxidant response.
De Backer J, Lin A, Berghe WV, Bogaerts A, Hoogewijs D
Redox biology 2022 Sep;55:102399
Redox biology 2022 Sep;55:102399
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Hiatt JB, Sandborg H, Garrison SM, Arnold HU, Liao SY, Norton JP, Friesen TJ, Wu F, Sutherland KD, Rienhoff HY, Martins R, Houghton AM, Srivastava S, MacPherson D
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Oct 14;28(20):4551-4564
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Oct 14;28(20):4551-4564
Cytoglobin Silencing Promotes Melanoma Malignancy but Sensitizes for Ferroptosis and Pyroptosis Therapy Response.
De Backer J, Maric D, Zuhra K, Bogaerts A, Szabo C, Vanden Berghe W, Hoogewijs D
Antioxidants (Basel, Switzerland) 2022 Aug 10;11(8)
Antioxidants (Basel, Switzerland) 2022 Aug 10;11(8)
B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy.
Zhao Y, Cao Y, Chen Y, Wu L, Hang H, Jiang C, Zhou X
Immunology 2021 Nov;164(3):507-523
Immunology 2021 Nov;164(3):507-523
Single-cell transcriptomics following ischemic injury identifies a role for B2M in cardiac repair.
Molenaar B, Timmer LT, Droog M, Perini I, Versteeg D, Kooijman L, Monshouwer-Kloots J, de Ruiter H, Gladka MM, van Rooij E
Communications biology 2021 Jan 29;4(1):146
Communications biology 2021 Jan 29;4(1):146
Impact of beta-2 microglobulin expression on the survival of glioma patients via modulating the tumor immune microenvironment.
Tang F, Zhao YH, Zhang Q, Wei W, Tian SF, Li C, Yao J, Wang ZF, Li ZQ
CNS neuroscience & therapeutics 2021 Aug;27(8):951-962
CNS neuroscience & therapeutics 2021 Aug;27(8):951-962
Enhanced β2-microglobulin binding of a "navigator" molecule bearing a single-chain variable fragment antibody for artificial switching of metabolic processing pathways.
Kambe Y, Kuwahara K, Sato M, Nakaoki T, Yamaoka T
Biomaterials science 2021 Aug 21;9(16):5551-5558
Biomaterials science 2021 Aug 21;9(16):5551-5558
β2-microglobulin as a biomarker of pulmonary fibrosis development in COPD patients.
Wu Z, Yan M, Zhang M, Wu N, Ma G, Wang B, Fan Y, Du X, Ding C, Liu Y
Aging 2020 Dec 21;13(1):1251-1263
Aging 2020 Dec 21;13(1):1251-1263
Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.
Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H
Nature communications 2018 Jan 30;9(1):433
Nature communications 2018 Jan 30;9(1):433
Heritable multiplex genetic engineering in rats using CRISPR/Cas9.
Ma Y, Shen B, Zhang X, Lu Y, Chen W, Ma J, Huang X, Zhang L
PloS one 2014;9(3):e89413
PloS one 2014;9(3):e89413
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 13511-1-AP(B2M antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human stomach cancer using 13511-1-AP(B2M antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Beta-2-microglobulin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Beta-2-microglobulin. This antibody recognizes human, mouse antigen. The Beta-2-microglobulin antibody has been validated for the following applications: ELISA, WB, IHC analysis.