NBP2-44470-0.1mg

antibody from Novus Biologicals
Targeting: B2M
Provider product page for NBP2-44470-0.1mg
Western blot
Immunocytochemistry
Flow cytometry

Antibody data

Product number
NBP2-44470-0.1mg - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal beta 2-Microglobulin Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. The antibody recognizes the hidden determinant of beta-2 microglobulin (i.e. binding to its determinant is available only when the chain is separated from the HLA heavy chain. beta-2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
Reactivity
Human, Simian
Host
Mouse
Isotype
IgG
Vial size
0.1 mg
Concentration
0.2 mg/ml
Storage
Store at 4C.
B2M protein structure - NBP2-44470-0.1mg shown in red.