Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-47700-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal beta 2-Microglobulin Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. Recognizes a protein of 12kDa, identified as beta-microglobulin. beta-microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
- Reactivity
- Human, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Flow Cytometry: beta 2-Microglobulin Antibody (246-E9.E7 (same as HLA.ABC.m2)) - Azide and BSA Free [NBP2-47700] - Flow Cytometric Analysis of PFA-fixed HeLa cells using beta 2-Microglobulin Antibody (246-E9.E7 (same as HLA.ABC.m2))followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red)