RA0377

antibody from Oursmab

Targeting: IL31 IL-31

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ELISA

Functional assay

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Validation data

Product number: RA0377 - Provider product page
Provider: Oursmab
Product name: Lokivetmab (Biosimilar Reference Antibody) (IL31)
Antibody type: Monoclonal
Description: Lokivetmab is a caninized monoclonal antibody specifically developed for veterinary use in dogs. It targets and neutralizes canine interleukin-31 (IL-31), a key pruritic (itch-inducing) cytokine. By binding to IL-31, lokivetmab blocks its interaction with the IL-31 receptor complex on sensory neurons and immune cells, thereby inhibiting the signaling pathway that triggers pruritus. It is approved (under the brand name Cytopoint?) for the treatment of canine atopic dermatitis, providing long-lasting relief from itching and associated inflammation with a monthly subcutaneous injection.
Reactivity: Canine
Isotype: IgG
Vial size: 100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
Concentration: Bottled at the concentration indicated on the vial.
Storage: Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

IL31 protein structure - RA0377 shown in red.