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- References [15]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13501-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13501-1-AP, RRID:AB_2112560
- Product name
- GPX7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GPX7 antibody (Cat. #13501-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GPX7 reduces chondrocyte inflammation and extracellular matrix degradation triggered by IL‑1β, via a mechanism mediated by ferroptosis.
Alginate oligosaccharide alleviates vascular aging by upregulating glutathione peroxidase 7.
A glycometabolic gene signature associating with immune infiltration and chemosensitivity and predicting the prognosis of patients with osteosarcoma.
GPX7 Is Targeted by miR-29b and GPX7 Knockdown Enhances Ferroptosis Induced by Erastin in Glioma.
GPX7 Facilitates BMSCs Osteoblastogenesis via ER Stress and mTOR Pathway.
GPx7 ameliorates non-alcoholic steatohepatitis by regulating oxidative stress.
The development of antioxidant system in the intestinal tract of broiler chickens.
Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling.
Glutathione peroxidase 7 suppresses cancer cell growth and is hypermethylated in gastric cancer.
Glutathione Peroxidase 7 Suppresses Bile Salt-Induced Expression of Pro-Inflammatory Cytokines in Barrett's Carcinogenesis.
GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum.
Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett's carcinogenesis.
Glutathione peroxidase 7 has potential tumour suppressor functions that are silenced by location-specific methylation in oesophageal adenocarcinoma.
Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human.
Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells.
Chen B, Fu W, Jie C, Zhang G, Li Z, Liu Y, Zhou S
Molecular medicine reports 2024 Jul;30(1)
Molecular medicine reports 2024 Jul;30(1)
Alginate oligosaccharide alleviates vascular aging by upregulating glutathione peroxidase 7.
Wang S, Yu Y, Liu J, Hu S, Shi S, Feng W, Mao Y
The Journal of nutritional biochemistry 2024 Apr;126:109578
The Journal of nutritional biochemistry 2024 Apr;126:109578
A glycometabolic gene signature associating with immune infiltration and chemosensitivity and predicting the prognosis of patients with osteosarcoma.
Wang F, Yang K, Pan R, Xiang Y, Xiong Z, Li P, Li K, Sun H
Frontiers in medicine 2023;10:1115759
Frontiers in medicine 2023;10:1115759
GPX7 Is Targeted by miR-29b and GPX7 Knockdown Enhances Ferroptosis Induced by Erastin in Glioma.
Zhou Y, Wu H, Wang F, Xu L, Yan Y, Tong X, Yan H
Frontiers in oncology 2021;11:802124
Frontiers in oncology 2021;11:802124
GPX7 Facilitates BMSCs Osteoblastogenesis via ER Stress and mTOR Pathway.
Hu X, Li B, Wu F, Liu X, Liu M, Wang C, Shi Y, Ye L
Journal of cellular and molecular medicine 2021 Nov;25(22):10454-10465
Journal of cellular and molecular medicine 2021 Nov;25(22):10454-10465
GPx7 ameliorates non-alcoholic steatohepatitis by regulating oxidative stress.
Kim HJ, Lee Y, Fang S, Kim W, Kim HJ, Kim JW
BMB reports 2020 Jun;53(6):317-322
BMB reports 2020 Jun;53(6):317-322
The development of antioxidant system in the intestinal tract of broiler chickens.
Tang D, Wu J, Jiao H, Wang X, Zhao J, Lin H
Poultry science 2019 Feb 1;98(2):664-678
Poultry science 2019 Feb 1;98(2):664-678
Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling.
Meng Q, Shi S, Liang C, Liang D, Hua J, Zhang B, Xu J, Yu X
Oncogene 2018 Nov;37(44):5843-5857
Oncogene 2018 Nov;37(44):5843-5857
Glutathione peroxidase 7 suppresses cancer cell growth and is hypermethylated in gastric cancer.
Chen Z, Hu T, Zhu S, Mukaisho K, El-Rifai W, Peng DF
Oncotarget 2017 Aug 15;8(33):54345-54356
Oncotarget 2017 Aug 15;8(33):54345-54356
Glutathione Peroxidase 7 Suppresses Bile Salt-Induced Expression of Pro-Inflammatory Cytokines in Barrett's Carcinogenesis.
Peng DF, Hu TL, Soutto M, Belkhiri A, El-Rifai W
Journal of Cancer 2014;5(7):510-7
Journal of Cancer 2014;5(7):510-7
GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum.
Ramming T, Hansen HG, Nagata K, Ellgaard L, Appenzeller-Herzog C
Free radical biology & medicine 2014 May;70:106-16
Free radical biology & medicine 2014 May;70:106-16
Loss of glutathione peroxidase 7 promotes TNF-α-induced NF-κB activation in Barrett's carcinogenesis.
Peng DF, Hu TL, Soutto M, Belkhiri A, El-Rifai W
Carcinogenesis 2014 Jul;35(7):1620-8
Carcinogenesis 2014 Jul;35(7):1620-8
Glutathione peroxidase 7 has potential tumour suppressor functions that are silenced by location-specific methylation in oesophageal adenocarcinoma.
Peng D, Hu T, Soutto M, Belkhiri A, Zaika A, El-Rifai W
Gut 2014 Apr;63(4):540-51
Gut 2014 Apr;63(4):540-51
Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human.
Chang YC, Yu YH, Shew JY, Lee WJ, Hwang JJ, Chen YH, Chen YR, Wei PC, Chuang LM, Lee WH
EMBO molecular medicine 2013 Aug;5(8):1165-79
EMBO molecular medicine 2013 Aug;5(8):1165-79
Glutathione peroxidase 7 protects against oxidative DNA damage in oesophageal cells.
Peng D, Belkhiri A, Hu T, Chaturvedi R, Asim M, Wilson KT, Zaika A, El-Rifai W
Gut 2012 Sep;61(9):1250-60
Gut 2012 Sep;61(9):1250-60
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 13501-1-AP(GPX7 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 13501-1-AP(GPX7 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GPX7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GPX7. This antibody recognizes human antigen. The GPX7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
