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LearnMAB2760
antibody from Novus Biologicals
Targeting: HCAR2
GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [2]
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- Product number
- MAB2760 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal HM74A/PUMA-G/GPR109A/NIACR1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human HM74A/GPR109A. Stains human HM74A/GPR109A-transfected cells but not irrelevant transfectants. Cross-reactivity with HM74 (GPR109B) was not tested.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.
Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A).
Singh N, Gurav A, Sivaprakasam S, Brady E, Padia R, Shi H, Thangaraju M, Prasad PD, Manicassamy S, Munn DH, Lee JR, Offermanns S, Ganapathy V
Immunity 2014 Jan 16;40(1):128-39
Immunity 2014 Jan 16;40(1):128-39
Neutrophil apoptosis mediated by nicotinic acid receptors (GPR109A).
Kostylina G, Simon D, Fey MF, Yousefi S, Simon HU
Cell death and differentiation 2008 Jan;15(1):134-42
Cell death and differentiation 2008 Jan;15(1):134-42
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of HM74A/PUMA-G/GPR109A in Human Blood Neutrophils by Flow Cytometry. Detection of HM74A/PUMA-G/GPR109A in Human Blood Neutrophils by Flow Cytometry.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of HM74A/PUMA-G/GPR109A in HEK293 Human Cell Line Transfected with Human HM74A/PUMA-G/GPR109A and eGFP by Flow Cytometry. Detection of HM74A/PUMA-G/GPR109A in HEK293 Human Cell Line Transfected with Human HM74A/PUMA-G/GPR109A and eGFP by Flow Cytometry.
