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- References [16]
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- Product number
- 21055-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21055-1-AP, RRID:AB_10695769
- Product name
- OXA1L antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OXA1L antibody (Cat. #21055-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A molecular switch in NAC prevents mitochondrial protein mistargeting by SRP.
A unified mechanism for mitochondrial damage sensing in PINK1-Parkin-mediated mitophagy.
Mitochondrial translation is a targetable dependency of chemo-refractory triple negative breast cancer.
Case Report: autosomal dominant distal motor neuropathy as a new phenotype of KIF21A-related disorders.
TANGO2 binds crystallin alpha B and its loss causes desminopathy.
Novel reporter of the PINK1-Parkin mitophagy pathway identifies its damage sensor in the import gate.
A molecular switch in NAC prevents mitochondrial protein mistargeting by SRP.
Four-Color STED Super-Resolution RNA Fluorescent In Situ Hybridization and Immunocytochemistry to Visualize Mitochondrial mRNAs in Context with Mitochondrial Ribosomes.
Translation of MT-ATP6 pathogenic variants reveals distinct regulatory consequences from the co-translational quality control of mitochondrial protein synthesis.
LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding.
Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation.
Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis.
OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect.
Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number.
Degradation of the deubiquitinating enzyme USP33 is mediated by p97 and the ubiquitin ligase HERC2.
Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.
Maldosevic E, Gora RJ, Lin LL, Zhou LE, Li ZJ, Peskova Y, Qi L, Shan SO, Jomaa A
Nature communications 2026 Mar 27;17(1)
Nature communications 2026 Mar 27;17(1)
A unified mechanism for mitochondrial damage sensing in PINK1-Parkin-mediated mitophagy.
Thayer JA, Petersen JD, Huang X, Gruel Budet LM, Hawrot J, Ramos DM, Sekine S, Li Y, Ward ME, Narendra DP
The EMBO journal 2026 Jan;45(1):64-105
The EMBO journal 2026 Jan;45(1):64-105
Mitochondrial translation is a targetable dependency of chemo-refractory triple negative breast cancer.
Berner MJ, Wall SW, Baek ML, Lane A, Greer AS, Wang K, Dobrolecki LE, Strope I, Zhu Q, Zhang B, Lei JT, Lewis MT, Echeverria GV
bioRxiv : the preprint server for biology 2026 Apr 18;
bioRxiv : the preprint server for biology 2026 Apr 18;
Case Report: autosomal dominant distal motor neuropathy as a new phenotype of KIF21A-related disorders.
Subbotin D, Tatarskiy E, Kuchina A, Cherevatova T, Krylova T, Ryzhkova O, Skoblov M, Murtazina A
Frontiers in genetics 2025;16:1699834
Frontiers in genetics 2025;16:1699834
TANGO2 binds crystallin alpha B and its loss causes desminopathy.
Stentenbach M, Hughes LA, Fagan SV, Payne B, Rudler DL, Siira SJ, McCubbin T, Chopin A, Perks KL, Ermer JA, Hendry J, Er TS, Balasubramaniam S, Eliades JA, Hool LC, Packer NH, Moh ESX, Padman BS, Rackham O, Filipovska A
Nature communications 2025 Jun 6;16(1):5261
Nature communications 2025 Jun 6;16(1):5261
Novel reporter of the PINK1-Parkin mitophagy pathway identifies its damage sensor in the import gate.
Thayer JA, Petersen JD, Huang X, Hawrot J, Ramos DM, Sekine S, Li Y, Ward ME, Narendra DP
bioRxiv : the preprint server for biology 2025 Feb 20;
bioRxiv : the preprint server for biology 2025 Feb 20;
A molecular switch in NAC prevents mitochondrial protein mistargeting by SRP.
Maldosevic E, Gora R, Lin LL, Zhou LE, Li ZJ, Peskova Y, Qi L, Shan SO, Jomaa A
bioRxiv : the preprint server for biology 2025 Aug 1;
bioRxiv : the preprint server for biology 2025 Aug 1;
Four-Color STED Super-Resolution RNA Fluorescent In Situ Hybridization and Immunocytochemistry to Visualize Mitochondrial mRNAs in Context with Mitochondrial Ribosomes.
Albus CA, Berlinguer-Palmini R, Chrzanowska-Lightowlers ZM, Lightowlers RN
Methods in molecular biology (Clifton, N.J.) 2023;2661:303-316
Methods in molecular biology (Clifton, N.J.) 2023;2661:303-316
Translation of MT-ATP6 pathogenic variants reveals distinct regulatory consequences from the co-translational quality control of mitochondrial protein synthesis.
Ng KY, Richter U, Jackson CB, Seneca S, Battersby BJ
Human molecular genetics 2022 Apr 22;31(8):1230-1241
Human molecular genetics 2022 Apr 22;31(8):1230-1241
LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding.
Shin CS, Meng S, Garbis SD, Moradian A, Taylor RW, Sweredoski MJ, Lomenick B, Chan DC
Nature communications 2021 Jan 11;12(1):265
Nature communications 2021 Jan 11;12(1):265
Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation.
Perks KL, Ferreira N, Ermer JA, Rudler DL, Richman TR, Rossetti G, Matthews VB, Ward NC, Rackham O, Filipovska A
Aging 2020 Oct 6;12(19):19677-19700
Aging 2020 Oct 6;12(19):19677-19700
Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis.
Lee RG, Gao J, Siira SJ, Shearwood AM, Ermer JA, Hofferek V, Mathews JC, Zheng M, Reid GE, Rackham O, Filipovska A
Journal of cell science 2020 Jul 24;133(14)
Journal of cell science 2020 Jul 24;133(14)
OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect.
Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW
EMBO molecular medicine 2018 Nov;10(11)
EMBO molecular medicine 2018 Nov;10(11)
Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number.
Thompson K, Majd H, Dallabona C, Reinson K, King MS, Alston CL, He L, Lodi T, Jones SA, Fattal-Valevski A, Fraenkel ND, Saada A, Haham A, Isohanni P, Vara R, Barbosa IA, Simpson MA, Deshpande C, Puusepp S, Bonnen PE, Rodenburg RJ, Suomalainen A, Õunap K, Elpeleg O, Ferrero I, McFarland R, Kunji ER, Taylor RW
American journal of human genetics 2016 Oct 6;99(4):860-876
American journal of human genetics 2016 Oct 6;99(4):860-876
Degradation of the deubiquitinating enzyme USP33 is mediated by p97 and the ubiquitin ligase HERC2.
Chan NC, den Besten W, Sweredoski MJ, Hess S, Deshaies RJ, Chan DC
The Journal of biological chemistry 2014 Jul 11;289(28):19789-98
The Journal of biological chemistry 2014 Jul 11;289(28):19789-98
Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.
Mishra P, Carelli V, Manfredi G, Chan DC
Cell metabolism 2014 Apr 1;19(4):630-41
Cell metabolism 2014 Apr 1;19(4):630-41
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 21055-1-AP(OXA1L antibody) at dilution of 1:800
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The OXA1L antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human OXA1L. This antibody recognizes human,mouse,rat antigen. The OXA1L antibody has been validated for the following applications: ELISA, WB analysis.
