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- References [13]
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- Product number
- 19218-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19218-1-AP, RRID:AB_10859824
- Product name
- SKIL antibody
- Antibody type
- Polyclonal
- Description
- SKIL antibody (Cat. #19218-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NSUN2 promotes colorectal cancer progression by enhancing SKIL mRNA stabilization.
Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids.
The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia.
BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease.
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.
Quantitative Ubiquitylome Analysis Reveals the Specificity of RNF111/Arkadia E3 Ubiquitin Ligase for its Degradative Substrates SKI and SKIL/SnoN in TGF-β Signaling Pathway.
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
PIAS1 and TIF1γ collaborate to promote SnoN SUMOylation and suppression of epithelial-mesenchymal transition.
SKIL facilitates tumorigenesis and immune escape of NSCLC via upregulating TAZ/autophagy axis.
The Transcriptional Regulator SnoN Promotes the Proliferation of Cerebellar Granule Neuron Precursors in the Postnatal Mouse Brain.
MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.
De novo GLI3 mutation in esophageal atresia: reproducing the phenotypic spectrum of Gli3 defects in murine models.
Zou S, Huang Y, Yang Z, Zhang J, Meng M, Zhang Y, Feng J, Sun R, Li W, Wang W, López JG, Fang L
Clinical and translational medicine 2024 Mar;14(3):e1621
Clinical and translational medicine 2024 Mar;14(3):e1621
Sumoylated SnoN interacts with HDAC1 and p300/CBP to regulate EMT-associated phenotypes in mammary organoids.
Chanda A, Sarkar A, Deng L, Bonni A, Bonni S
Cell death & disease 2023 Jul 7;14(7):405
Cell death & disease 2023 Jul 7;14(7):405
The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia.
Amhaz S, Boëda B, Chouchène M, Colasse S, Dingli F, Loew D, Henri J, Prunier C, Levy L
BMC biology 2023 Apr 7;21(1):73
BMC biology 2023 Apr 7;21(1):73
BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease.
Peng W, Zhou X, Xu T, Mao Y, Zhang X, Liu H, Liang L, Liu L, Liu L, Xiao Y, Zhang F, Li S, Shi M, Zhou Y, Tang L, Wang Y, Guo B
Cell death & disease 2022 Mar 21;13(3):254
Cell death & disease 2022 Mar 21;13(3):254
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.
Wu ZL, Chen YJ, Zhang GZ, Xie QQ, Wang KP, Yang X, Liu TC, Wang ZQ, Zhao GH, Zhang HH
Apoptosis : an international journal on programmed cell death 2022 Feb;27(1-2):133-148
Apoptosis : an international journal on programmed cell death 2022 Feb;27(1-2):133-148
Quantitative Ubiquitylome Analysis Reveals the Specificity of RNF111/Arkadia E3 Ubiquitin Ligase for its Degradative Substrates SKI and SKIL/SnoN in TGF-β Signaling Pathway.
Laigle V, Dingli F, Amhaz S, Perron T, Chouchène M, Colasse S, Petit I, Poullet P, Loew D, Prunier C, Levy L
Molecular & cellular proteomics : MCP 2021;20:100173
Molecular & cellular proteomics : MCP 2021;20:100173
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Zhang J, Zou L, Shi D, Liu J, Zhang J, Zhao R, Wang G, Zhang L, Ouyang L, Liu B
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
Song AN, Yin XJ, Gao P, Tang H, Meng XF, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
PIAS1 and TIF1γ collaborate to promote SnoN SUMOylation and suppression of epithelial-mesenchymal transition.
Chanda A, Ikeuchi Y, Karve K, Sarkar A, Chandhoke AS, Deng L, Bonni A, Bonni S
Cell death and differentiation 2021 Jan;28(1):267-282
Cell death and differentiation 2021 Jan;28(1):267-282
SKIL facilitates tumorigenesis and immune escape of NSCLC via upregulating TAZ/autophagy axis.
Ma F, Ding MG, Lei YY, Luo LH, Jiang S, Feng YH, Liu XL
Cell death & disease 2020 Dec 2;11(12):1028
Cell death & disease 2020 Dec 2;11(12):1028
The Transcriptional Regulator SnoN Promotes the Proliferation of Cerebellar Granule Neuron Precursors in the Postnatal Mouse Brain.
Chen X, Chanda A, Ikeuchi Y, Zhang X, Goodman JV, Reddy NC, Majidi SP, Wu DY, Smith SE, Godec A, Oldenborg A, Gabel HW, Zhao G, Bonni S, Bonni A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jan 2;39(1):44-62
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019 Jan 2;39(1):44-62
MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling.
Tang H, Lei CT, Ye C, Gao P, Wan C, Chen S, He FF, Wang YM, Su H, Zhang C
Journal of cellular and molecular medicine 2017 Dec;21(12):3435-3444
Journal of cellular and molecular medicine 2017 Dec;21(12):3435-3444
De novo GLI3 mutation in esophageal atresia: reproducing the phenotypic spectrum of Gli3 defects in murine models.
Yang L, Shen C, Mei M, Zhan G, Zhao Y, Wang H, Huang G, Qiu Z, Lu W, Zhou W
Biochimica et biophysica acta 2014 Sep;1842(9):1755-61
Biochimica et biophysica acta 2014 Sep;1842(9):1755-61
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SKIL antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SKIL. This antibody recognizes human, mouse, rat antigen. The SKIL antibody has been validated for the following applications: ELISA, WB analysis.
