NB100-64340
C8A antibody from Novus Biologicals
- Western blot
Data presented on provider website
- ELISA
Data presented on provider website
- Immunohistochemistry
Data presented on provider website
- Flow cytometry
Data presented on provider website
Antibody data
- Antibody Data
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- NB100-64340
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-64340, RRID:AB_960759
- Product name
- Mouse Monoclonal Complement C8A/B/G Antibody
- Provider product page
- Novus Biologicals - NB100-64340
- Antibody type
- Monoclonal
- Description
- Protein A purified. This antibody recognizes complement component 8 (C8), a 151 kDa member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyzes the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane. Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.