Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 23778-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ADAM8 antibody
- Antibody type
- Polyclonal
- Description
- ADAM8 antibody (Cat. #23778-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The GBM Tumor Microenvironment as a Modulator of Therapy Response: ADAM8 Causes Tumor Infiltration of Tams through HB-EGF/EGFR-Mediated CCL2 Expression and Overcomes TMZ Chemosensitization in Glioblastoma.
Suppression of ADAM8 attenuates angiotensin II-induced cardiac fibrosis and endothelial-mesenchymal transition via inhibiting TGF-β1/Smad2/Smad3 pathways.
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
ADAM8 Activates NLRP3 Inflammasome to Promote Cerebral Ischemia-Reperfusion Injury.
Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR.
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
Translation control of the immune checkpoint in cancer and its therapeutic targeting.
High ADAM8 expression is associated with poor prognosis in patients with hepatocellular carcinoma.
Liu X, Huang Y, Qi Y, Wu S, Hu F, Wang J, Shu K, Zhang H, Bartsch JW, Nimsky C, Dong F, Lei T
Cancers 2022 Oct 7;14(19)
Cancers 2022 Oct 7;14(19)
Suppression of ADAM8 attenuates angiotensin II-induced cardiac fibrosis and endothelial-mesenchymal transition via inhibiting TGF-β1/Smad2/Smad3 pathways.
Yao L, Shao W, Chen Y, Wang S, Huang D
Experimental animals 2022 Feb 9;71(1):90-99
Experimental animals 2022 Feb 9;71(1):90-99
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, Künzel SR, Kämmerer S, Günscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L, Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M, El-Armouche A
Nature communications 2022 Dec 10;13(1):7648
Nature communications 2022 Dec 10;13(1):7648
ADAM8 Activates NLRP3 Inflammasome to Promote Cerebral Ischemia-Reperfusion Injury.
Lu H, Meng Y, Han X, Zhang W
Journal of healthcare engineering 2021;2021:3097432
Journal of healthcare engineering 2021;2021:3097432
Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR.
Chen ZH, Luo XC, Yu CR, Huang L
Molecular and cellular neurosciences 2020 Oct;108:103552
Molecular and cellular neurosciences 2020 Oct;108:103552
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
Li W, Wang D, Sun X, Zhang Y, Wang L, Suo J
International journal of molecular medicine 2019 Feb;43(2):914-926
International journal of molecular medicine 2019 Feb;43(2):914-926
Translation control of the immune checkpoint in cancer and its therapeutic targeting.
Xu Y, Poggio M, Jin HY, Shi Z, Forester CM, Wang Y, Stumpf CR, Xue L, Devericks E, So L, Nguyen HG, Griselin A, Gordan JD, Umetsu SE, Reich SH, Worland ST, Asthana S, Barna M, Webster KR, Cunningham JT, Ruggero D
Nature medicine 2019 Feb;25(2):301-311
Nature medicine 2019 Feb;25(2):301-311
High ADAM8 expression is associated with poor prognosis in patients with hepatocellular carcinoma.
Zhang Y, Tan YF, Jiang C, Zhang K, Zha TZ, Zhang M
Pathology oncology research : POR 2013 Jan;19(1):79-88
Pathology oncology research : POR 2013 Jan;19(1):79-88
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- BxPC-3 cells were subjected to SDS PAGE followed by western blot with 23778-1-AP( ADAM8 Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ADAM8 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ADAM8. This antibody recognizes human, mouse antigen. The ADAM8 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
