DLX2

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2. [provided by RefSeq, Jul 2008]

Description

distal-less homeobox 2

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas), Transcription factors

Chromosome

2:q31.1 (172099438 - 172102900)

Ensembl ID

ENSG00000115844  (ver. 99.38)

Orthologs

Mouse Dlx2: ENSMUSG00000023391

UniProt

Q07687

neXtProt

NX_Q07687

Human splice variants
Mouse splice variants