Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 66117-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- ECHS1 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated ECHS1 antibody (Cat. #66117-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2B9D5
- Vial size
- 20ul, 150ul
Submitted references Valine and Inflammation Drive Epilepsy in a Mouse Model of ECHS1 Deficiency.
ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation.
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement.
Up-regulation of fatty acid oxidation in the ligament as a contributing factor of ankylosing spondylitis: A comparative proteomic study.
Eller MM, Zuberi AR, Fu X, Burgess SC, Lutz CM, Bailey RM
bioRxiv : the preprint server for biology 2024 Jun 13;
bioRxiv : the preprint server for biology 2024 Jun 13;
ECHS1, an interacting protein of LASP1, induces sphingolipid-metabolism imbalance to promote colorectal cancer progression by regulating ceramide glycosylation.
Li R, Hao Y, Wang Q, Meng Y, Wu K, Liu C, Xu L, Liu Z, Zhao L
Cell death & disease 2021 Oct 6;12(10):911
Cell death & disease 2021 Oct 6;12(10):911
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
Li Z, Shen W, Wu G, Qin C, Zhang Y, Wang Y, Song G, Xiao C, Zhang X, Deng G, Wang R, Wang X
FEBS open bio 2021 Jul;11(7):1893-1906
FEBS open bio 2021 Jul;11(7):1893-1906
Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement.
Haack TB, Jackson CB, Murayama K, Kremer LS, Schaller A, Kotzaeridou U, de Vries MC, Schottmann G, Santra S, Büchner B, Wieland T, Graf E, Freisinger P, Eggimann S, Ohtake A, Okazaki Y, Kohda M, Kishita Y, Tokuzawa Y, Sauer S, Memari Y, Kolb-Kokocinski A, Durbin R, Hasselmann O, Cremer K, Albrecht B, Wieczorek D, Engels H, Hahn D, Zink AM, Alston CL, Taylor RW, Rodenburg RJ, Trollmann R, Sperl W, Strom TM, Hoffmann GF, Mayr JA, Meitinger T, Bolognini R, Schuelke M, Nuoffer JM, Kölker S, Prokisch H, Klopstock T
Annals of clinical and translational neurology 2015 May;2(5):492-509
Annals of clinical and translational neurology 2015 May;2(5):492-509
Up-regulation of fatty acid oxidation in the ligament as a contributing factor of ankylosing spondylitis: A comparative proteomic study.
Xu WD, Yang XY, Li DH, Zheng KD, Qiu PC, Zhang W, Li CY, Lei KF, Yan GQ, Jin SW, Wang JG
Journal of proteomics 2015 Jan 15;113:57-72
Journal of proteomics 2015 Jan 15;113:57-72
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 66117-1-Ig(ECHS1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ECHS1 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human ECHS1. This antibody recognizes human antigen. The ECHS1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
