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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Product number
- ABIN182546 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-HES1 antibody
- Antibody type
- Polyclonal
- Antigen
- The immunogen for anti-HES1 antibody: synthetic peptide directed towards the N terminal of human HES1
- Reactivity
- Human, Mouse, Rat, Bovine, Chicken/Avian, Porcine, Xenopus
- Host
- Rabbit
- Antigen sequence
NTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQ
LKTLI LDALKKDSSR- Vial size
- 0.1 mg
Submitted references Overexpression of hCLP46 enhances Notch activation and regulates cell proliferation in a cell type-dependent manner.
Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling.
Notch signaling promotes growth and invasion in uveal melanoma.
Notch signalling is off and is uncoupled from HES1 expression in Ewing's sarcoma.
hCLP46 regulates U937 cell proliferation via Notch signaling pathway.
The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.
Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells.
Chu Q, Liu L, Wang W
Cell proliferation 2013 Jun;46(3):254-62
Cell proliferation 2013 Jun;46(3):254-62
Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling.
Guiu J, Shimizu R, D'Altri T, Fraser ST, Hatakeyama J, Bresnick EH, Kageyama R, Dzierzak E, Yamamoto M, Espinosa L, Bigas A
The Journal of experimental medicine 2013 Jan 14;210(1):71-84
The Journal of experimental medicine 2013 Jan 14;210(1):71-84
Notch signaling promotes growth and invasion in uveal melanoma.
Asnaghi L, Ebrahimi KB, Schreck KC, Bar EE, Coonfield ML, Bell WR, Handa J, Merbs SL, Harbour JW, Eberhart CG
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Feb 1;18(3):654-65
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Feb 1;18(3):654-65
Notch signalling is off and is uncoupled from HES1 expression in Ewing's sarcoma.
Bennani-Baiti IM, Aryee DN, Ban J, Machado I, Kauer M, Mühlbacher K, Amann G, Llombart-Bosch A, Kovar H
The Journal of pathology 2011 Nov;225(3):353-63
The Journal of pathology 2011 Nov;225(3):353-63
hCLP46 regulates U937 cell proliferation via Notch signaling pathway.
Ma W, Du J, Chu Q, Wang Y, Liu L, Song M, Wang W
Biochemical and biophysical research communications 2011 Apr 29;408(1):84-8
Biochemical and biophysical research communications 2011 Apr 29;408(1):84-8
The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
Schreck KC, Taylor P, Marchionni L, Gopalakrishnan V, Bar EE, Gaiano N, Eberhart CG
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Dec 15;16(24):6060-70
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Dec 15;16(24):6060-70
Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.
Tilley AE, Harvey BG, Heguy A, Hackett NR, Wang R, O'Connor TP, Crystal RG
American journal of respiratory and critical care medicine 2009 Mar 15;179(6):457-66
American journal of respiratory and critical care medicine 2009 Mar 15;179(6):457-66
Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells.
Hoebeke I, De Smedt M, Van de Walle I, Reynvoet K, De Smet G, Plum J, Leclercq G
Blood 2006 Apr 1;107(7):2879-81
Blood 2006 Apr 1;107(7):2879-81
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