Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL1070 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-CIR1 monoclonal antibody, clone 3F22
- Antibody type
- Monoclonal
- Description
- CIR1 (corepressor interacting with RBPJ, 1) is a protein-coding gene. Diseases associated with CIR1 include cryptococcosis, and meningoencephalitis, and among its related super-pathways are Notch signaling pathway and Development NOTCH1-mediated pathway for NF-KB activity modulation. GO annotations related to this gene include RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding transcription factor activity. May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3F22
- Storage
- Store at -2°C or lower. Aliquot to avoid repeated freezing and thawing.
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